ERARD · Emotion regulation in adolescents at risk for depression
„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“
- Период
- 2019-03-20 → 2023-08-31
- Финансиране от ЕС
- 263 385 €
- Участници
- 2
- Схема
- MSCA-IF
Линиите свързват координатора с партньорите.
Накратко на български
Реакциите на мозъка на деца от 9 до 13 години се проследяват чрез ЯМР скенер, докато те слушат критика или похвали от майките си и от връстници. Това помага да се разберат механизмите за регулиране на емоциите при деца с риск от депресия.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Emotion regulation in adolescents at risk for depression
ERARD focuses on better understanding mechanisms that contribute to the development of psychopathology, and specifically depression. Depression is a highly prevalent and often recurrent emotional disorder that is characterized with difficulties downregulating negative mood and sustaining or upregulating positive mood. One of the main risk factors to developing depression is having a mother with a history of depression. Indeed, there is some evidence that children of mothers with a history of depression have more difficulties regulating their emotions compared with children of mothers without a history of depression. Additionally, there is some evidence that abnormal brain reactions are related to these difficulties. However, most studies on emotion regulation in children of mothers with depression ignored the social context, which plays a central role in emotional responding and in depression development.To address the limitations in the literature ERARD focused on comparing social-emotional responses of adolescent children (aged 9-13) of mothers with and without a history of depression. To examine social-emotional responses children were asked to listen to critical, neutral, and praising comments said by their mother and by a child their own age and gender. Children listened to these pre-recorded statements while going through a functional Magnetic Resonance Imaging (fMRI) scan, which showed us how the brain reacted to different statements. After completing the brain scan children completed a 28-day long daily diary, which is a short survey asking about their emotions, social experiences, and depressive symptoms.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
This project will examine whether deficient emotion regulation (ER) in response to interpersonal events is a vulnerability factor for MDD First, we will examine whether, compared to controls, at-risk individuals (a) respond to criticism with higher negative affect (NA), greater activation in brain areas related to NA, and less activation in brain areas related to ER, and (b) respond to praise with lower positive affect (PA) and less activation in brain areas related to experiencing pleasure. Second, using experience sampling methods (ESM), we will examine whether, compared to controls, at-risk individuals (a) respond to negative interpersonal events with higher NA and deficient ER strategies, and (b) respond to positive interpersonal events with lower PA and deficient ER strategies. Then, we will examine whether neural activation in response to interpersonal stimuli in the lab predicts affective responses to everyday interpersonal experiences. Finally, gender differences will be assessed. The sample will include 50 children of mothers with a history of MDD and a control group of 50 children of never-disordered mothers. In the first lab visit participants will complete a diagnostic interview. In the second lab visit participants will complete questionnaires assessing depression and ER strategies, an fMRI scan while listening to a recording of critical remark and praising remarks from one’s mother. Finally, they will receive training in the computerized experience-sampling diary. The diary electronic device will prompt participants 4 times a day for 14 days and will assess daily positive and negative interpersonal events, mood, and ER strategies. The examination of deficient ER in response to interpersonal events as a vulnerability factor for depression development is innovative and important. The combination of neuroimaging with ESM is a unique opportunity to translate lab findings to everyday life.
Оригинален текст от CORDIS (на английски).
Участници
- TEL AVIV UNIVERSITY · Tel AvivКоординаторИзраел
- YALE UNIVERSITY · New HavenСъединени щати
Връзки
Данни: CORDIS, © Европейски съюз