ARIADNE · Structure and dynamics in active glass-forming liquids
„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“
- Период
- 2019-06-01 → 2021-05-31
- Финансиране от ЕС
- 160 932 €
- Участници
- 1
- Схема
- MSCA-IF-EF-ST
Линиите свързват координатора с партньорите.
Накратко на български
Активните системи, като бактериалните колонии, се изследват, за да се разбере как частиците се движат и взаимодействат чрез нетоплинна енергия. Тези данни създават основа за по-добро разбиране на сложните биологични среди.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Structure and dynamics in active glass-forming liquids
Transport in passive systems such as molecular liquids is controlled by temperature. In contrast, active systems such as bacterial colonies present a new control parameter in the form of a non-thermal energy. This energy, used by active particles to drive their motion, is accompanied by a variety of particle features, including different shapes and interactions. It is unclear how this scenario conditions transport and phase transitions in these systems. The overall aim of this project is to characterise this transport for a collection of models of active systems using molecular dynamics simulations and experimental techniques. This investigation is conceived to provide a foundation, based on canonical models and specially designed experiments, for exploring complex biological environments. This project introduces many original aspects such as the use of a novel mixed methodology, including coarse grained models, a repertoire of statistical tools, and the use of experimental techniques so far employed in passive systems. This mixing of different techniques and disciplines favours an innovative transfer of knowledge between physicists and biologists. The project also promotes some of the aspirations of the MSCA: the engagement of the general public through a pedagogical dissemination and the establishment of interdisciplinary interchanges. This project is included in an emergent field of fundamental research resulting from combining different disciplines such as statistical physics and microbiology. These hybrid collaborations have shown great impact, reaching different expert audiences and bringing new perspectives to problems that were tackled from a single perspective. Thus, this project has created a networking initiative, involving different departments at the University of Granada, collaborations with companies, and connections with other international institutions. With this project we have also considered some of the challenges promoted by the United Nations: the development of resilient and diversified human structures to foster innovation. As overall objectives, this project considered the study of transport in real systems and computational models with: isotropic interactions, non-isotropic interactions, and polarity. Despite the original objectives of this project (in particular those concerning experiments) have strongly suffered from the situation created by the COVID-19, this action has concluded with significant results: i) all the computational models were developed; ii) despite the lockdown arriving to Spain at the end of the first third of the action, I obtained promising experimental results; iii) I published a research paper as leading scientist in Physical Review X (the journal with the second highest impact factor, 15.762, publishing research in all areas of physics), and have three papers in preparation; iv) I developed a network of collaborations of different kind: local, international, interdisciplinary, and inter-sectoral; v) I communicated my results in international conferences, and in internal and external seminars; vi) I disseminated my expertise by: teaching courses at an undergraduate level, considering the gender dimension through activities with secondary schools, and being present in the media.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
In this project I plan to investigate the transition between a liquid state and a disordered solid-like state in systems of active particles using numerical simulations and experimental approaches. In contrast to equilibrium (passive) systems, where this transition is controlled by temperature and/or density, active systems incorporate a new control parameter in the form of a locally-absorbed energy of non-thermal origin. Thus, with this investigation, I propose an extension to the canonical Glass Transition (GT) problem to non-equilibrium, actively-stimulated, systems. Active interplay between liquid and solid states manifests in real systems such as the cytoplasm of animal cells, dense bacterial colonies, tissues, and packed crowds. However, despite the deep biological implications, it is unclear how the presence of non-thermal energy affects the emergence of the GT in these systems. This will be the first time that this problem will be addressed with a collection of representative models of active systems. Using molecular dynamics simulations of variable complexity, I will consider part of the rich variety of features present in real active particles. This will include shape, polarity, and anisotropy. I will also explore how these features influence the emergence of collective active behaviour. These computational approaches will be accompanied by an uncommon interplay of experimental techniques which will serve to contrast computational results. I will study rheological material properties and characterise the emergence of the glass solidness for active systems using suspensions of colloids and bacteria. To extend the experimental characterisation to a microscopic level, I will use diffusive wave spectroscopy and optical microscopy. With this novel and comprehensive investigation, I aim to provide a foundation for exploring much more complex biological environments, where distinct primary entities coexist and cooperate.
Оригинален текст от CORDIS (на английски).
Участници
- UNIVERSIDAD DE GRANADA · GranadaКоординаторИспания
Връзки
Данни: CORDIS, © Европейски съюз
