H2020Индивидуална стипендия2020–2023

SUPERTEFF · A new paradigm in boosting orphan crops to super grains: Linking metabolomics and gene editing to improve Teff for global food security and sustainable agriculture

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2020-03-25 → 2023-01-22
Финансиране от ЕС
224 934 €
Участници
1
Схема
MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Етиопската култура теф се изследва чрез генетично редактиране и анализ на метаболитите, за да се превърне в по-продуктивна храна. Диверсификацията на такива „забравени“ култури помага за подобряване на хранителната сигурност и устойчивостта на земеделието при променящ се климат.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

A new paradigm in boosting orphan crops to super grains: Linking metabolomics and gene editing to improve Teff for global food security and sustainable agriculture

With increasing urbanization and climate change it is predicted that there will be a global crisis in the future agricultural systems by 2050 due to the increase in demand for staple food crops. To reduce the gap between the food supply and demand, sustainable agriculture and food security is one of the targeted priorities. Over the past decade’s improvement strategies are focused on staple crops like wheat, rice and maize. But this will not be an effective solution to meet the future requirements of the growing global population where different parts of the world have different growing conditions and needs. Considering this, one strategy to alleviate these pressures is through the diversification of minor or "orphan crops”. These crops have the advantages that they are nutritious and are more responsive to a rapidly changing environment with more productivity but often they have received less attention from the research community. Major calorie consumption of human diet comes from the cereals and of the many edible cereals there are a category of niche crops (millets and Teff), where they have been exploited only for their nutritional benefits and is being gaining demand as functional foods in the Western countries at the same time there is a need to tackle the malnutrition in Africa and Asia by improving their staple food crops. This current project targets an emerging Ethiopian cereal, Teff that has received less research attention. Teff is a tiny-seeded Ethiopian crop and serve as a staple food for over 50 million people in the Horn of Africa. It is recently gaining prominence in the food market because of its gluten-free nature and high-levels of proteins, minerals (iron and calcium), flavonoids (antioxidants) vitamins and slow-digestible starch and is an alternative for people suffering from gluten intolerance and type 2 diabetes. Tef is found to thrive in a wide range of environmental conditions such as drought and water logging. Despite its nutritional and resilience nature, tef has lower yield due to lack of sustained research and development efforts that limits its contribution towards global food and nutrition security. The characteristics of teff make it an excellent candidate for bio-fortification and crop improvement and to further develop this under-utilized/studied species as a sustainable crop for research led agricultural growth. Overall aim of SUPERTEFF project is to augment the value of this neglected crop into a 'super grain' by applying various high-throughput omics approaches. This involves the novel application of phenomics and metabolomics based studies followed by the implementation of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system in exploring the potential of this crop for human food and animal feed. Taking this forward, for the first time, a large collection of teff varieties will be screened using wide range of genome and metabolite approaches.The proposed study will identify elite teff lines with better yield and nutritional quality which will further help the Ethiopian farmers and breeders in their tef breeding and improvement programmes.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Food security is one of the prime concerns of the world as the production is affected by increase in demand for cereal crops as food and bioenergy resources. In order to maximize productivity, one strategy is to identify and improve indigenous crops (orphan crops) which are often ignored. Orphan crops (e.g. teff, millet) possess better nutritional and adaptive traits than other cereal crops (e.g. rice, wheat). Teff, Ethiopia’s most important indigenous cereal crop is recently gaining attention among farmers and consumers over other cereals due to its natural gluten-free nature and its adaptation to tough environmental conditions. The high market price for its grains and straw make it a valuable cash crop but has received less attention on research and funding. The main objective of “SUPERTEFF” is to apply omics and gene editing strategies for the improvement of teff. The key objectives of the study are (1) characterization of disparate teff germplasm for agronomically important traits using image-based phenomics (2) to explore the nutrient diversity in teff cultivars using high-throughput metabolomics (3) metabolite-genome-wide association studies (m-GWAS) to understand the genotype to phenotype relation (4) to develop a CRISPR/Cas9 gene editing platform in teff with prime focus to lodging. The proposed study will provide a new paradigm in linking metabolic status to gene expression and will provide valid targets for CRISPR gene editing strategies in teff to convert it from an orphan crop to a super crop which will bare comparison to other established cereal crops. The outputs of this project will result in bridging the gap between orphan crops and other cereal crops in terms of sustainable yield and resilience to environmental conditions, whereby addressing the growing concerns of farmers and consumers across the globe. This project aims to strengthen the EU economy, by placing it in the fore-front of global food security and sustainable agriculture.

Оригинален текст от CORDIS (на английски).

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Връзки

Данни: CORDIS, © Европейски съюз