H2020Индивидуална стипендия2020–2022

DIGDEEP · Digging deeper into genes to track infectious disease outbreaks

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2020-09-01 → 2022-08-31
Финансиране от ЕС: 203 149 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Вирусите на птичия грип се проследяват чрез генетичен анализ, за да се разбере как се предават между дивите птици, домашните птици и хората. Това помага за определяне на броя на незабелязаните случаи и създаване на по-ефективни стратегии за контрол на болестта.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Digging deeper into genes to track infectious disease outbreaks

The DIGDEEP project aims to unravel the transmission dynamics of avian influenza viruses (AIV) at the poultry-wild bird-human interface, by using an original combination of epidemiological and phylodynamic approaches. Through the DIGDEEP project, our core goal is to generate underpinning knowledge needed to develop effective control strategies tailored to the characteristics of AIV evolution and transmission and informing health policy making. In particular, the outcomes of the DIGDEEP project are (i) the inference of key epidemiological parameters of AIV spread, such as the basic reproduction number, (ii) the quantification of spillover events between host species and (iii) the estimation of the number of unreported cases, which are crucial for a well-informed response.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Successful public and animal health interventions require detailed knowledge of infectious disease transmission dynamics, in particular how they spread within and between populations. Recent advances in phylodynamics have largely contributed towards the understanding of epidemic spread, including Ebola, HIV and MERS-CoV, by integrating epidemiological and genetic data. Since the beginning of the 21st century, the emergence of new avian influenza viruses (AIV) with high pandemic potential have underlined the need for established global mechanisms to respond to public and animal health threats. To this end, DIGDEEP aims at developing alternative control strategies tailored to the characteristics of AIV evolution and transmission in order to minimize the global economic and health impact of the epidemics. The project will use cutting-edge phylodynamic inference methods to explore devastating and unprecedented epidemics of AIV in Europe and Asia. The outcomes of the project will allow us to infer key epidemiological parameters of the virus spread, such as the basic reproduction number or the likelihood of spillover between host species, and characterize the determinants of the epidemics, such as the importance of population structure or super-spreaders. DIGDEEP will also help to assess the effectiveness of public and animal health interventions in bringing the epidemic under control which are crucial for a well-informed response. Throughout the project, the fellow will gain a strong experience in phylodynamic inference methods, complementing her experience in epidemiology of infectious disease transmission. DIGDEEP will consolidate her scientific expertise in the field of public and animal health and develop transferable skills in team-working, communication and project management, which will be paramount to boost her career as a successful and internationally-recognized researcher.

Оригинален текст от CORDIS (на английски).

Участници

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH · ZuerichКоординаторШвейцария