H2020Съфинансиране2020–2024

ARCAID · Amsterdam Rheumatology Center for AutoImmune Diseases

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2020-01-01 → 2024-12-31
Финансиране от ЕС: 2 169 600 €
Участници: 1
Схема: MSCA-COFUND

Линиите свързват координатора с партньорите.

Накратко на български

Автоимунните ревматични заболявания се изучават чрез анализ на молекулярни механизми и биопроби от хора и мишки. Това помага за подобряване на диагностиката и създаването на персонализирано лечение за пациенти с възпаления в опорната система.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Amsterdam Rheumatology Center for AutoImmune Diseases

Autoimmune rheumatic diseases are characterized by inflammation, affecting connecting or supporting structures of the body and lead to disabling and painful conditions affecting the quality of life, loss of (work-) productivity and high costs. It is hard to translate understanding of the immunological processes to improved diagnostics or therapeutic healthcare interventions. ARCAID aims to be a top-class research institute where ESRs will be skilled through excellent training programs set up along four trivial pillars in translational research; I. Application of state-of-the-art technologies on human and murine biosamples; II. Delineating the molecular and cellular mechanisms underlying pathophysiology of disease; III. Development of improved computational procedures for data analysis and interpretation; IV. Discovery of novel markers to improve diagnostics, prognostics and therapy response to aid the development of personalised medicine. In conclusion, ARCAID ESRs have shown great progress, showing both expected and unexpected results that contributed to new directions, methodological innovations that will support science efforts world-wide, and potential impacts in science, medicine, and in the wider socio-economic context. All fellows will receive their PhD, enhancing their job opportunities in Europe and beyond.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Autoimmune rheumatological diseases such as rheumatoid arthritis, spondyloarthritis, vasculitis and systemic lupus erythematosus continue to exert significant tolls on the quality of life of millions of afflicted patients and on European societies in the form of loss of (work-)productivity and costs. Major advances in our understanding of the immunological processes underlying these diseases have been made, but it has not always been possible to translate these to improved diagnostics or therapeutic health care interventions. At the AMC and collaborating institutions and partners, we have developed the translational platforms for true bench-to-bedside development of the next generation of diagnostics and therapeutics for these diseases. To contribute to this effort, the next generation of scientists that work on translational immunological rheumatology need to be educated. Therefore, a multidisciplinary research team of scientists based at several faculties at Amsterdam UMC, The Netherlands are applying for a Marie Skłodowska-Curie COFUND grant. In this programme, 20 PhD students will work in the field of translational immunological rheumatology. The ARCAID applicants at the Amsterdam UMC consist of leading and renowned research groups on this subject and we are confident that these groups can achieve the ambitious goals of the program.

Оригинален текст от CORDIS (на английски).

Участници

STICHTING AMSTERDAM UMC · AmsterdamКоординаторНидерландия