H2020Индивидуална стипендия2021–2023

MICRODEV · Microplastics: morphological and genetic developmental effects in a marine invertebrate.

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-03-01 → 2023-09-15
Финансиране от ЕС: 183 473 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Микропластмасите и техните генетични и физически ефекти върху развитието на морските безгръбначни се анализират чрез модел с морски ежи. Резултатите ще помогнат за разбирането на вредите от пластмасовото замърсяване върху животните и екосистемите в океана.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Microplastics: morphological and genetic developmental effects in a marine invertebrate.

Fifty trillion microplastic particles are floating in the sea. Although microplastics alter the development of a range of marine invertebrates, the consequences of these developmental effects are likely underestimated, and the effects for ecosystems are unknown. No systematic studies have characterized the range of developmental defects elicited by microplastic contamination on marine invertebrates. Using the sea urchin Paracentrotus lividus as a model, this project aimed at: (1) explore the morphological and genetic consequences of microplastic exposure on development; (2) identify which characteristics of the plastic particles cause the effects; (3) assess if the effects are specific, altering developmental pathways, or a consequence of general toxicity. This multidisciplinary, novel work will transform our understanding of the effects of microplastic contamination on development, including the underlying genetic mechanisms, and their implications for other animals exposed to MP contamination. Plastic waste is a topic of major societal interest, and media coverage around plastics and marine pollution suggests that this project is of great interest to the general public, and is meant to help stakeholders (fishermen/farmers and third sector (NGOs) along with plastic manufacturers) and regulatory bodies avoid damage to stocks and livelihoods.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Plastic debris contamination is a growing environmental concern in marine habitats. Large plastic objects break-up over time to create micro- and nano- particles, collectively called microplastics (MP), which account for the overwhelming majority of plastic particles in the sea. Little is known about the impacts of MP on wildlife or humans and this presents an important research priority. Several studies have demonstrated that MP can affect sea life negatively. Amongst these, they have been reported affecting development (causing malformations, delayed growth and increased death rates). These developmental effects have never been characterised, and their molecular basis remains unknown. Developmental defects may impact population survival by decreasing the number of individuals, or their fitness, in range of marine organisms.This pioneering project will identify the effects of MP exposure in the development of the sea urchin Paracentrotus lividus, bridging interests for ecology, toxicology, developmental biology and aquaculture. I will characterise the developmental morphological malformations caused by MP and their underlying genetic mechanisms.This Fellowship will provide an excellent opportunity to complement my strong background in genetics and molecular and developmental biology and expertise in ecotoxicology and microplastic pollution with transcriptomic analysis and the deep understanding of this model organism for development and toxicology under the supervision of Dr. Arnone, a world leading expert in the field. This will provide me with a firm skill set and knowledge to further my research career. The knowledge and expertise I will acquire in the Arnone lab, together with being hosted by a supportive and acclaimed institution, and the prestige of the MSCA fellowship, will allow me to open a unique and timely line of research and will be crucial for my transition into an independent European researcher.

Оригинален текст от CORDIS (на английски).

Участници

STAZIONE ZOOLOGICA ANTON DOHRN · NapoliКоординаторИталия