H2020Индивидуална стипендия2020–2022

CHRONOTRADE · Clock-mediated modulation of growth-defense trade-offs and its potential as a biotechnological tool

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2020-04-01 → 2022-03-31
Финансиране от ЕС: 172 932 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Биологичният часовник на растенията регулира баланса между техния растеж и защитата им от вредители. Разбирането на този механизъм може да помогне за повишаване на добивите от културите и развитието на устойчиво земеделие.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Clock-mediated modulation of growth-defense trade-offs and its potential as a biotechnological tool

In light of current estimates on world population growth, a key challenge in the agriculture and food systems is the need to sustainably improve agricultural productivity to meet the increasing demand, as identified by the FAO in its 2017 report. Growth-defense trade-offs represent a major paradigm in ecological studies, and the balance between both physiological programs is theorized to impact plant productivity in both natural and agricultural ecosystems. Within this framework, the main objective of the project was to characterize a molecular circuit, which is likely involved in the modulation of growth-defense trade-offs in plants, to ultimately be able to modify it and use it as a biotechnological strategy for crop productivity improvement and sustainable agriculture.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Circadian clocks are conserved time-tracking mechanisms that allow organisms to align endogenous physiological processes with the changing environment. Growing evidence supports a role for these biological clocks, not only as mere timekeepers, but as pivotal regulators of extensive cellular networks. In plants, the influence of the clock on development and physiology is pervasive and many traits of agronomical value are subjected to circadian regulation. Noteworthy, clock gene alleles have been traditionally selected because of their desirable influences on key agricultural traits.An outstanding clock protein that functions at the interface between the clock and its output is GIGANTEA (GI). We propose to investigate this regulatory hub protein, and characterize the molecular mechanism by which it modulates the balance between growth and defense. Knowledge gained from the model plant Arabidopsis will be transferred to a crop species (tomato) in order to establish a framework for targeted biotechnological manipulation. Consequently, an innovative strategy based on edgetic alleles will be deployed to generate new GI alleles that uncouple growth from defense, a key feature for cultivated species.From a training point of view, this fellowship will build on the Experienced Researcher’s (ER) solid expertise on molecular biology and complement it with the skills required to translate basic research to tackle specific agronomical issues. This will undoubtedly boost her opportunities to reach an independent research position with biotechnological orientation.In summary, this proposal aims to (i) advance our understanding on the connections between the clock and its output in model and crop species, (ii) generate novel variants of circadian-clock components as a biotechnological strategy for sustainable agriculture, and (iii) render a well-trained academic researcher with the capacities needed to develop a professional career within biotechnological research.

Оригинален текст от CORDIS (на английски).

Участници

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS · MadridКоординаторИспания