H2020Индивидуална стипендия2021–2023

RESPIMMOX · UnRaveling the molEcular baSis Promoting Candidatus BrocadIa as the doMinant anaMOX genus in wastewater treatment plants

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-03-01 → 2023-02-28
Финансиране от ЕС: 162 806 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Бактериите от рода Candidatus Brocadia се изследват, за да се разбере защо те доминират при пречистването на отпадни води. Познаването на техните молекулярни характеристики помага за повишаване на ефективността и стабилността на пречиствателните станции.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

UnRaveling the molEcular baSis Promoting Candidatus BrocadIa as the doMinant anaMOX genus in wastewater treatment plants

The global water demands have triggered a vast generation of wastewater that can end up contaminating water bodies. Water pollution is already disrupting economies and people’s life worldwide. Nowadays, nitrogen removal from wastewater is based on energy demanding processes. However, the finding of anammox bacteria brought up the possibility of achieving energy-self-sufficient wastewater treatment plants. When anammox processes are implemented, the aeration costs are reduced because of the lower oxygen requirements of the process compared to conventional systems and biogas production can be increased since most of the organic matter can be destined to an anaerobic digestion process. Nevertheless, despite their ubiquity and key denitrifying role in nature, and the manifest interest of implementing anammox-based processes by industry, the widespread technological application of anammox processes is still under research and there is a critical absence of molecular studies to understand how the anammox bacteria make a living. One of the current challenges of anammox bacteria research is to understand niche differentiation. The overall objective of the RESPIMMOX project is to understand the biomolecular characteristics of anammox Ca. Brocadia that trigger their niche differentiation as the main anammox genus present in wastewater treatment plants. The results from this proposal will entail a step forward for understanding the dominance of Ca. Brocadia in bioreactors (key to improve efficiency and stability) and will contribute to unravel the puzzle that anammox bacteria pose.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The finding of anammox bacteria brought up the possibility of achieving energy-self-sufficient wastewater treatment plants for nitrogen removal, but their widespread technological application is still under research. The lack of pure cultures, standard cultivation methods and comprehensive genetic data make the molecular research on anammox bacteria challenging, and thus, there is a critical absence of molecular studies to understand how these bacteria make a living. One of the current challenges of anammox bacteria research is to understand niche differentiation, meaning how and why different anammox species find their unique ecological space. RESPIMMOX project aims to understand the biomolecular characteristics of anammox Ca. Brocadia that trigger their niche differentiation as the main anammox genus present in wastewater treatment plants, to improve the efficiency and stability of bioreactors. We will obtain biochemical evidence of the membrane-bound protein complexes involved in the electron transport chain of Brocadia-species, and investigate the soluble yet-unidentified enzymes responsible of the nitrite reduction. We will follow a complexome profiling approach combined with enzymatic activity assays, as commonly performed with Dehalococcoides mccartyi in the host laboratory. RESPIMMOX project will be accomplished through three specific objectives: i) achievement of an anammox Brocadia-enriched culture with high cell concentrations; ii) training of the researcher in biochemical methods to characterize respiratory complexes using the respiration with halogenated aromatic compounds as an example; and iii) identification and characterization of the protein complexes involved in the anammox Ca. Brocadia energy metabolism. The results from this proposal will entail a step forward for the understanding of anammox niche differentiation, specifically of the dominance of Ca. Brocadia in bioreactors, and will contribute to unravel the puzzle that anammox bacteria pose.

Оригинален текст от CORDIS (на английски).

Участници

HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ · LeipzigКоординаторГермания