Sensor4Diabetes · Hybrid sensor for diabetes detection from exhaled breath using nanoparticles loaded 1D metal oxides
„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“
- Период
- 2020-10-01 → 2022-11-01
- Финансиране от ЕС
- 224 934 €
- Участници
- 1
- Схема
- MSCA-IF
Линиите свързват координатора с партньорите.
Накратко на български
Хибридни сензори с наночастици се разработват за откриване на диабет чрез анализ на издишания въздух. Неинвазивният метод за ранна диагностика може да намали тежките здравословни усложнения и разходите за здравеопазване.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Hybrid sensor for diabetes detection from exhaled breath using nanoparticles loaded 1D metal oxides
Traditionally, blood glucose is monitored to diagnose diabetes via invasive and painful techniques. In recent years, minimally invasive glucose sensing mechanisms such as continuous glucose monitoring (CGM) devices have been developed to alert an individual before they begin experiencing low or high level of blood glucose. The sensors in the CGM system are implanted underneath the skin and require frequent calibration, which need to be replaced frequently. This operation is highly inconvenient and this device is very expensive. Therefore, there is a high demand for non-invasive, affordable and rapid detection devices for continuous monitoring of diabetes, which is searched by the researchers worldwide. Early and affordable diabetes detection technology for monitoring and management of diabetes will help hundreds of thousands people to reduce serious health problems and life threatening side effects. The ‘Sensor4Diabetes’ project aims to develop non-invasive impedometric and photonic based hybrid sensors for detecting and monitoring diabetes from exhaled breath. According to the International Diabetes Federation (IDF), in 2021 worldwide about 537 million people in the 20-79 age range had diabetes and estimated to be 783 million by the year of 2045. Diabetes is responsible for 6.7 million deaths in 2021. Due to the increased incidence, the associated healthcare expenditure has risen to 918 billion Euros in 2021 and estimated to be 998 billion Euros by 2045. Worldwide governments are struggling to cover the cost of diabetes. The outcomes of this project will be actions which can readily be implemented to speed the early identification of the disease for saving health services billions of Euros annually and significantly improve lives. ‘Sensor4Diabetes’ targets achieving early identification and thus better monitoring of diabetes. This project will open doors for further studies and innovation action, not only in Europe but also in other countries and in the developing world, to inspire the innovators to further develop suitable tools for people of all groups, different ethnicities, races, ages and social status. The project addresses several of the key UN Sustainable Development Goals (such as Goal 1 ‘erasing poverty’; Goal 9, promoting ‘innovation’ (involving developing countries as well); Goal 10, ‘reducing inequality’ and most importantly Goal 3 (‘Health’). The overall objective of ‘Sensor4Diabtes’ project is to develop novel hybrid breath analysing sensor based on semiconducting metal oxide nanostructures to diagnose diabetes by employing both impedometric and photonic methods. The main drive of the breath sensor is to provide miniaturize, continuous, real-time, non-invasive and mobile device for detection and monitoring of diabetes at a lower cost.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Health and well-being has been one of the kHealth and well-being has been one of the key societal and grand challenges identified in EC Research and Innovation programs. Diabetes is one of the most prevailing chronic health problems across Europe and worldwide. Diabetic patients experience painful blood glucose testing in daily basis which is highly inconvenient. Replacement of blood testing with non-invasive methods would bring a paradigm shift in diabetes management. Human exhaled breath consists of several traces of volatile organic compounds (VOCs) known as “breath marker”. The presence of increased amount of acetone, ethanol and methyl nitrate has been confirmed in diabetic breath by various sophisticated techniques which are not suitable for routine clinical practice or domestic use due to their non-portability, complexity, bulk-size and high costs. Metal oxide sensors have considerable potential in detecting VOCs in exhaled breath. For VOCs analysis in breath requires high sensitivity together with high selectivity. The aim of this project is to develop hybrid sensor for analyzing VOCs in breath from 1D metal oxide nanostructures functionalized with different catalytic nanoparticles. Both impedometric and photonic properties of the sensors will be measured in presence of synthetic healthy and synthetic diabetic breath. The 1D metal oxide nanostructures on sensing platform could provide high surface-to-volume ratio for surface adsorption/desorption of gas molecules together with excellent electronic and optical properties. The addition of catalytic nanoparticles on the surface of 1D nanostructures will enhance the sensitivity and response time towards VOCs by lowering the oxidation energy, increasing the catalytic surface area and catalytic activation of gas molecules. It is expected that adoption of hybrid sensing principle will enhance the selectivity towards individual VOCs which is essential for the development of highly effective diabetic breath analyzer.
Оригинален текст от CORDIS (на английски).
Участници
- CITY ST GEORGES UNIVERSITY OF LONDON · LONDONКоординаторОбединеното кралство
Връзки
Данни: CORDIS, © Европейски съюз
