H2020Индивидуална стипендия2021–2023

REMAp · Adaptive and personalized neuromotor rehabilitation of persons with Multiple Sclerosis: from characterization to exploitation of residual sensorimotor abilities using a body-machine interface

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-01-04 → 2023-01-03
Финансиране от ЕС: 171 473 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Интерфейсите „тяло-машина“ се тестват при хора с рассеяна склероза, за да помогнат за управлението на външни устройства чрез остатъчната мускулна активност. Това помага за по-доброто разбиране на заболяването и подобряване на двигателната рехабилитация.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Adaptive and personalized neuromotor rehabilitation of persons with Multiple Sclerosis: from characterization to exploitation of residual sensorimotor abilities using a body-machine interface

Multiple sclerosis (MS) is one of the world’s most common neurologic disorders. It is a chronic progressive disease that leads to deficits of motor, sensory and cognitive functions. Rehabilitation is a key element for people with Multiple Sclerosis (PwMS) to mantain and maximize their motor functions, and technology-aided neurorehabilitation approaches have been proved to overcome some limits of traditional treatments. In particular, body-machine interfaces (BoMIs) seem very promising. With BoMIs it is possible to exploite the abundance of muscles and degrees of freedom of the motor apparatus, providing for a high level of dexterity that even with a progressive neurologic disease like MS is not totally lost, but is still enough to be used by the BoMI to empower the user to interact with the environment controlling external devices in an efficient way. The problems addressed in REMAp are: 1) lack of precise and sensitive tools to evaluate and treat upper limb sensorimotor impairment after MS; 2) BoMI never been tested with PwMS; 3) no studies investigated neural correlates of motor training in MS in a complete manner, from muscle to brain; 4) lack of evidence of modifications in proprioception after BoMI training. Filling these gaps is important for society because it will advance the state of the art helping better understanding the pathophysiology of the disease and to advance the state of the art of BoMIs and rehabilitation after MS. Overall objectives: O1 - To design and implement a BoMI that integrates muscle activity and motion signals for personalized motor training of people with MS O2 - To identify and understand changes in the organization of the central and peripheral nervous system in response to BoMI rehabilitative interventions in MS O3 - To assess if a BoMI training enhancing the exploration of new movement coordination patterns has a positive impact on proprioception

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The project AIMS AT developing and validating a novel approach to neuromotor rehabilitation of persons with Multiple Sclerosis (PwMS), rooted in the physiological mechanisms of recovery and based on Body-Machine Interfaces (BoMI). This project is INNOVATIVE in that it explicitly takes subjects’ impairments into account, first characterizing it and then inherently adapting and individualizing the rehabilitative interventions. The project is based on the IDEA that after a neurologic disease or during a rehabilitative training all the nervous system (from the periphery to the brain) go through a reorganization and knowing these changes can be exploited to design more effective and tailored intervention. Muscle synergies in combination with kinematic synergies will be used to develop a MS- specific tool for a complete functional evaluation, to monitor progress of the disease and effects of treatments, and they will be use to design a BoMI that will exploit the residual mobility with patient-specific exercises helping PwMS to reach their full functional potential. Because of their adaptive nature, BoMIs will benefit PwMS with different degrees of impairment adapting to their changing conditions (worsening due to the disease progress or improving due to therapy). The project will evaluate BoMI training-induced reorganization in the brain and spinal cord with innovative imaging techniques. This will allow building solid foundations for a comprehensive understanding of use-dependent plasticity of the sensorimotor cortex and sensorimotor tracts in healthy subject and in PwMS. The expected outcome will be a novel method and a class of highly adaptive, personalized devices that not only maximize the restoration of functional performance, but also promote the functional reorganization of body abilities.

Оригинален текст от CORDIS (на английски).

Участници

UNIVERSITA DEGLI STUDI DI GENOVA · GENOVAКоординаторИталия