H2020Докторантска мрежа2020–2025

RENOIR · REcreating the ideal Niche: environmental control Of cell Identity in Regenerating and diseased muscles

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2020-05-01 → 2025-04-30
Финансиране от ЕС
3 482 325 €
Участници
14
Схема
MSCA-ITN

Линиите свързват координатора с партньорите.

Накратко на български

Мускулните клетки и тяхната среда се анализират, за да се разбере как се губят маса и функция при стареене и болести. Това помага за подобряване на качеството на живот на хората с хронични заболявления и възрастно население.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

REcreating the ideal Niche: environmental control Of cell Identity in Regenerating and diseased muscles

The project aims to address one of the major challenges in Europe that is to have an ageing population, which is healthy and active, and to improve the quality of life of people affected by chronic diseases. Skeletal and cardiac muscle ischemia are amongst the major causes of exacerbation of several diseases and morbidity in the population that represent an important social and economic burden for our society. In this context, the overall objective of RENOIR research program is to unravel, the decline in skeletal and cardiac muscle mass and function during ageing and disease, using advanced biotechnological tools. Specific scientific objectives of the project are to identify molecular signatures and interaction patterns of muscle niche components and to combine biomaterials and biopharma for improved ex vivo models and in vivo regeneration. The project innovations will provide a strong basis for the growth of the involved biotechnology company.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

RENOIR is a European Training Network that brings together 12 beneficiaries (10 academic and 2 industrial), and 3 partner organizations (a private Onlus Foundation, a pharmaceutical company, and a university) to train 13 Early Stage Researchers with an interdisciplinary profile for outstanding carriers as leaders in the field of muscle regeneration and aging. Receiving a training programme in both scientific and transferable skills and using unique expertise and tools at the frontier between biology and engineering, this new generation of versatile researchers will dissect the cellular and molecular mechanisms underlying impaired muscle composition and function, paving the way to new therapeutic interventions for muscle disease and aging. This will happen through collaborative and synergistic projects between academia and industry.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз