H2020Обмен на изследователи2021–2026

CompSafeNano · NanoInformatics Approaches for Safe-by-Design NanoMaterials

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2021-09-01 → 2026-08-31
Финансиране от ЕС
1 642 200 €
Участници
27
Схема
MSCA-RISE

Линиите свързват координатора с партньорите.

Накратко на български

Наноинформатичните модели предвиждат как наноматериалите взаимодействат с околната среда и дали са токсични за човека. Това помага за създаването на по-безопасни продукти в медицината и енергетиката, като същевременно подобрява регулациите за тяхната употреба.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

NanoInformatics Approaches for Safe-by-Design NanoMaterials

The CompSafeNano project addresses critical challenges in the safe design and regulatory readiness assessment of nanomaterials (NMs). As the application of NMs grows across sectors like pharmaceuticals, energy, agriculture and manufacturing, ensuring these materials are safe for humans and the environment is essential. Traditional methods lack the precision and scalability required for comprehensive risk assessment of NMs. CompSafeNano seeks to develop advanced, integrated nanoinformatics models that accurately predict NM interactions, toxicity, and environmental impact. NMs offer immense potential to revolutionize technology and industry, but the lack of robust, universally applicable safety guidelines risks adverse human health and environmental impacts. CompSafeNano benefits society by facilitating safer, more sustainable innovations in nanotechnology, by implementing safety-by-design (SbD) strategies and validating them for regulatory compliance, thereby building public and regulatory confidence in nanotechnology, thus supporting the responsible advance of this field. CompSafeNano has two main goals: 1. Development of universally applicable nanoinformatics models that can be employed directly by industry and regulators to predict risks, guide safety assessments, and support decision-making regarding NMs. 2. Enhancing skill levels in nanoinformatics among researchers through comprehensive training and knowledge transfer initiatives. This objective addresses the current gap in expertise necessary for advancing safe-by-design methodologies in nanotechnology.​

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The unique properties of nanomaterials (NMs), relative to their bulk form, has seen them used in a rapidly increasing number of commercial applications. However, with these useful new properties of NMs come potential health and environmental hazards. Thus, as part of a responsible innovation approach, NMs potential risks must be assessed in parallel to exploitation of their benefits. Due to their enormous variability, NM risk assessment urgently needs advanced in silico methodologies capable of machine learning from limited experimental datasets. These in silico tools for NMs characterisation, exposure, hazard and risk assessment and sustainability and life cycle assessment, need to support implementation of existing regulatory guidelines and extend regulatory risk assessment to integrate the extensive new knowledge generated computationally. CompSafeNano’s overarching objective is thus to drive the development of integrated and universally applicable nanoinformatics models, with broad domains of applicability across NMs compositions and forms, that are directly usable by industry, especially SMEs, and regulators for NMs risk assessment and decision making. CompSafeNano will establish an extended safe-by-design paradigm that includes environmental sustainability (life cycle assessment) based on in silico predictions with experimental testing to validate the results. CompSafeNano has a clear set of objectives to deliver this vision of an in silico safe-by-design computational platform and will be in close communication with other EU projects to access existing data on NM hazard and integrate existing nanoinformatics and NMs risk governance platforms (i.e. within NanoCommons, NanoSolveIT & RiskGONE). Training activities will benefit both ESRs and ERs from participating organizations, with a strong focus on inter-sectoral exchange (SME-academia) and international collaboration, filling the well-recognised current skills gap in nanoinformatics and big data analytics.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз