H2020Индивидуална стипендия2021–2023

Pain_App · Predicting neuropathic pain episodes in spinal cord injury patients through portable EEG and machine learning

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-04-01 → 2023-03-31
Финансиране от ЕС: 203 852 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Биосигналите от преносими ЕЕГ устройства се анализират чрез машинно обучение, за да се предвидят епизоди на невропатической болка при пациенти с увреждане на гръбначния стълб. Това помага за определяне на интензитета на болката и подобряване на ефективността на индивидуалното лекарствено лечение.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Predicting neuropathic pain episodes in spinal cord injury patients through portable EEG and machine learning

Neuropathic pain (NP) is a common symptom arising as a direct consequence of a lesion or disease affecting the somatosensory system. The traditional approach to managing NP patients is to initiate treatment with conservative pharmacological therapy before interventional strategies. However, first-line drug treatments have shown modest efficacy with less than 50% of pain relief. Since NP is present in ~70% of patients with spinal cord injury (SCI), people with this pathology represent a reliable population to study NP. Interestingly, previous studies have shown a clear correlation between NP and changes in electroencephalography (EEG), which is a good indicator of the state of the central nervous system. Characterized and developed technology to calculate NP would have a great impact on the quality of life of the patients. Personalized pharmacological treatments would increase their efficacy. PAIN_App is built in state-of-the-art digital health technology (a smartphone app, smartwatch, and a portable EEG) and aims to identify the biosignals that determine the intensity of NP in SCI. Based on initial analysis, the data collected has shown a moderate correlation to some features of the EEG, however, more analysis are currently being conducting

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Neuropathic pain (NP) is a common symptom arising as a direct consequence of a lesion or disease affecting the somatosensory system. The traditional approach to manage NP patients is to initiate treatment with conservative pharmacological therapy before interventional strategies. However, first-line drug treatments have shown modest efficacy with less than 50% of pain relief. Since NP is present in ~70% of patients with spinal cord injury (SCI), people with this pathology represent a reliable population to study NP. Interestingly, previous studies have shown a clear correlation between NP and changes in electroencephalography (EEG), which is a good indicator of the state of the central nervous system. Hence, I hypothesise that NP episodes in SCI patients can be predicted based on the classification and identification of features extracted from EEG recordings in resting state and during an imaginary motor task. In recent years, digital health technology has emerged as a useful tool to improve data management strategy under the full control of the patient. In this project, I will employ state-of-the-art digital health technology (a smartphone app and a portable EEG) to collect data from SCI patients daily for one month, including pain self-assessment scales and physiological indicators. I will set up a digital-health-based study using a software platform already established by the host institution. The collection of these data will allow me to develop a personalised model to predict the onset of NP episodes using machine learning techniques. Predicting the occurrence of NP episodes will increase the medication efficacy, which in turn will prevent an aggressive development of pain events while minimising the side effects produced by excessive drug doses. The expected results of this project will remarkably improve the quality of life of SCI patients with NP.

Оригинален текст от CORDIS (на английски).

Участници

MALMO UNIVERSITET · MALMOEКоординаторШвеция