H2020Индивидуална стипендия2022–2024

DECORE · Decoding the molecular control of bud dormancy release in trees

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2022-01-01 → 2024-03-26
Финансиране от ЕС: 203 852 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Молекулярните механизми, които контролират събуждането на пъпките при хибридния осика, се анализират чрез взаимодействието между гени и хормони. Това помага да се разбере как дърветата усещат температурата и се адаптират към сезонните промени в околната среда.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Decoding the molecular control of bud dormancy release in trees

• What is the problem/issue being addressed? Plants lack a nervous system and central decision-making organ, but can nevertheless sense and respond to environmental cues, including seasonal cues that play crucial roles in regulating their growth and development, through poorly understood mechanisms. By exploring the interplay between gene expression, hormonal regulation, and cell-cell communication, we elucidated the mechanisms underlying the temperature-mediated control of bud dormancy. In this project we have provided an important insight into the molecular regulation of dormancy and the mechanism underlying seasonally aligned growth in trees by temperature. • Why is it important for society? In this project we have identified the role of AGL8-GA module in mediating PD opening and provided an important insight into the molecular regulation of dormancy and the mechanism underlying seasonally aligned growth in trees by temperature. This research project revealed the mysteries behind bud dormancy in trees by investigating the interactions between genes, hormones, and cell-cell communication. These findings will advance our understanding of how plants adapt to seasonal changes and contribute to the competitiveness of European research, particularly in the field of developmental adaptation to seasonal variations. • What are the overall objectives? This project aims to elucidate the molecular mechanisms underlying the temperature-mediated control of bud dormancy in the experimental model tree hybrid aspen. In this project we functionally characterized an unknown MADS-box transcription factor AGL8, which was previously identified in the host lab. In this project we focused on (1) If FT1 is a direct downstream target of AGL8 and AGL8-mediated FT1 activation is required for low temperature (LT) induced dormancy release, (2) If AGL8 is a LT-responsive transcriptional regulator of GA biosynthesis in buds, and if AGL8-mediated LT-induced GA biosynthesis is essential for LT-induced dormancy release, and (3) Whether AGL8 promotes dormancy release by transcriptionally activating the expression of GH17 endoglucanases which are believed to catalyse callose breakdown and a subsequent PD opening.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Plants lack a nervous system and central decision-making organ like a brain, but can nevertheless sense and respond to environmental cues that play crucial roles in regulating their growth, through poorly understood mechanisms. The aim of DECORE is to elucidate these mechanisms, particularly those underlying the low temperature-mediated control of bud dormancy in the model tree hybrid aspen. A recent discovery in the host lab, pinpointing AGL8 as a low temperature responsive transcription factor involved in bud dormancy release, has lead us to hypothesize that AGL8-mediated transcriptional control of the plant hormone gibberellin, mobile signaling component FT1 (a tree ortholog of Arabidopsis FLOWERING LOCUS T) and cell-cell communication together orchestrate bud dormancy release. In DECORE, Dr. Pandey will test this hypothesis by deciphering the interplay between gene expression, hormonal regulation and cell-cell communication during dormancy release, and simultaneously acquire skills in cutting-edge techniques like transmission electron microscopy, immunocytochemistry and mass spectrometry in leading environments at the host SLU/UPSC (Umeå, Sweden) and via secondment to CNRS (Bordeaux, France). Synergistically complementing the skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Pandey with a unique opportunity to broaden his technical and theoretical expertise, which will promote a successful achievement of the project’s goals, open new vistas in developmental adaptation, and support his ambition of becoming a research leader. Dr. Pandey will follow a personalized career development plan to enhance his skills in communication, grant writing, public engagement and student mentoring. Thus, DECORE will contribute fundamental knowledge on a key process in seasonal adaptation, critical for mitigating the effects of climate change on seasonal growth in trees, and career advancement of a scientist with outstanding potential.

Оригинален текст от CORDIS (на английски).

Участници

SVERIGES LANTBRUKSUNIVERSITET · UppsalaКоординаторШвеция