H2020Индивидуална стипендия2021–2023

FPNP-BioLED · Fluorescent Protein-metal oxide NanoParticles for Bio-hybrid Light-Emitting Diodes

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-09-01 → 2023-08-31
Финансиране от ЕС: 162 806 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Флуоресцентни протеини, капсулирани в силициеви наночастици, се тестват за използване в био-хибридни светодиоди. Това подобрява стабилността и чистотата на цвета на светлината, дори при работа на висока мощност.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Fluorescent Protein-metal oxide NanoParticles for Bio-hybrid Light-Emitting Diodes

The project aimed to enhance the stability of fluorescent proteins (FPs) within Bio-High-Efficiency Lighting Emitting Diodes (Bio-HLEDs) by developing hybrid nanomaterials based on FPs encapsulated in silica (FP@SiO2/MOx). Unfortunately, the goal of creating a double-shell structure wasn't achieved due to the inherent instability of the proteins. Consequently, our research shifted its focus toward the development of SiO2 hybrid materials. Our primary objectives were to pioneer innovative techniques for encapsulating FPs within silica nanoparticles (FP@SiO2) to enhance their stability and optical properties. We devised two innovative approaches: one involved the supramolecular modification of carboxylic acid groups, while the other utilized silyl ester functionalization under physiological conditions. These methods resulted in the creation of highly stable monochromatic and dual-emissive FP@SiO2 nanoparticles.These nanoparticles demonstrated exceptional stability and optical properties, even under challenging conditions and in organic solvents. In Bio-HLEDs, coatings with FP@SiO2 achieved complete conversion with high color purity and demonstrated remarkable stability under high-power conditions.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

White light-emitting diodes (WLEDs) are the future of the artificial illumination promising to reduce 20% of the global electricity consumption in 2025. Nowadays, the main concern of the WLED technology is its sustainable development with respect to the inorganic phosphors (IPs) due to toxicity, environmental hazardousness, scarcity, high costs, and lack of efficient recycling protocols. In this context, bio-hybrid WHLEDs (Bio-WHLED) is emerging as a solid alternative showing how to replace IPs for sustainable fluorescent protein (FPs) embedded in a polymer matrix. In detail, Bio-WHLEDs take advantage of highly emissive blue, green, and red FPs that are stabilized into a rigid or elastomeric polymeric matrix over years under ambient storage and over months under device operation conditions. One of the main challenges towards stable and efficient Bio-WHLEDs consists in the difficult control of spatial distribution of FPs, which implies nonefficient energy transfer processes related to the distance in the polymeric matrix. Moreover, the overheating of Bio-WHLEDs related to the free motion of FP into the polymer matrix leads to the melting of the polymeric matrix and the quick photobleaching of the FPs due to the H-transfer deactivation of the chromophore under continuous excitation. To circumvent these limitations, we propose to develop highly efficient and stable Bio-WHLEDs using single-layered color filters with new white-emitting core-shell FP-nanoparticles (FPNP), in which a white-emitting core in the form of either a mixture of FPs or oligomeric white FPs is protected by a double shell of silica/metal oxide that will simultaneously avoid heat generation (protein motion) and H-transfer processes.

Оригинален текст от CORDIS (на английски).

Участници

TECHNISCHE UNIVERSITAET MUENCHEN · MuenchenКоординаторГермания