H2020Индивидуална стипендия2021–2023

BioResORGEL · Bioresorbable Organic Electronic Devices

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2021-08-20 → 2023-08-19
Финансиране от ЕС: 203 852 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Органичните електронни устройства се разработват така, че да се разграждат напълно, например при временни импланти за регенерация на периферни нерви. Това помага за намаляване на отпадъците от електрониката и избягва рискови операции за изваждане на медицински устройства от тялото.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Bioresorbable Organic Electronic Devices

Conventional electronics, including consumers products and medical devices, mostly rely on metal-oxide semiconductors such as silicon, germanium, etc., which are difficult and expensive to dispose of. As electronics become increasingly integrated in of our daily lives, there is a growing demand for technologies that decompose after a period of stable operation without leaving a permanent mark. For consumers electronics, such as smart packaging, solutions that are based on organic and resorbable materials are set to contribute towards the sustainability target to reduce waste and promote the manufacture of greener products. In the biomedical field, bioresorbable devices prospect to advance temporary implants, such as bioelectronic interfaces for peripheral nerve regeneration after injury (affecting over 730´000 people/year in the EU), where device resorption has the advantage to make risky secondary surgical procedures for device retrieval unnecessary. The aim of the BioResOrgel project was to develop materials and devices that provide stable operation as required for applications and that completely resorb in the body after service life. Bioresorbable materials have the potential to provide a new stream of electronic devices that completely degrade after having completed their function, thereby advancing applications, such as temporary medical implants and consumers electronics. The research was carried out at the Kungliga Tekniska Högskolan (KTH) under the supervision of Professor Anna Herland.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Bioresorbable bioelectronics aim to produce technologies that monitor/modulate biological functions and safely integrate into life and the environment. It prospects to eliminate the need for bioelectronic implants retrieval and to produce zero waste solutions for consumer electronics.The integration of degradable substrates with water-soluble electronic components (metals and semiconductors) led to the first examples of bioresorbable electronic implants. A key challenge is to develop devices combining high performance, stable operation, and controlled degradation at the end of their life cycle. Current hydrolysable materials suffer from inadequate lifetime, uncontrolled bulk degradation, and/or poor performance. Advanced bioresorbable microelectronics would require components that degrade in biological environments by the action of enzymes – something that cannot be achieved with conventional metal-oxide semiconductors. Conjugated polymers offer transport of both ions and electrons, low operating voltages, and flexibility – features exploited to improve state-of-the-art bioelectronic devices and interfaces – and, most importantly, the potential to undergo enzymatic breakdown. Yet, there is currently no example of a conjugated polymer and device thereof combining all the required properties.This project develops the first example of bioresorbable organic bioelectronic devices that are degraded in situ by the action of specific enzymes. It integrates aspects from materials chemistry (polymer design), organic electronics (device design), and cellular biology (biodegradation and toxicity). Key focus is to integrate device components that provide high performance and that are eroded by enzymes normally secreted by immune cells during inflammation and tissue regeneration. This interdisciplinary approach suggests a promising future across different fields – from fundamental aspects of polymers degradation and toxicity to the next generation bioelectronic interfaces.

Оригинален текст от CORDIS (на английски).

Участници

KUNGLIGA TEKNISKA HOEGSKOLAN · StockholmКоординаторШвеция