Меню
КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
HEИндивидуална стипендия2022–2024

INVERT2ADAPT · Chromosomal inversions in Atlantic herring and adaptation to changing sea water temperature

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период
2022-07-01 → 2024-06-30
Финансиране от ЕС
222 662 €
Участници
1
Схема
HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Хромозомните инверсии при атлантическата херинга показват как промените в ДНК помагат на рибата да се адаптира към различните температури на морската вода. Това помага да се разбере какви генетични механизми позволяват на природните популации да оцеляват при променяща се среда.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Chromosomal inversions in Atlantic herring and adaptation to changing sea water temperature

Large chromosomal inversions have been increasingly linked to local adaptation in natural populations. Despite their importance, there is current debate about what evolutionary forces maintain inversion polymorphisms in natural populations, particularly regarding the interplay between balancing and divergent selection. Furthermore, limitations of sequencing technologies often result in poor characterization of inversion breakpoints obscuring our understanding of their functional impact. This project focuses on Atlantic herring (Clupea harengus) as a model system to study the contribution of chromosomal inversions to local adaptation using multiple genomics tools.The project is divided in three work packages with the following aims: 1) Characterize the chromosomal inversions and date their origin relatively to the evolutionary history of Atlantic herring using comparative genomics and phylogenomics; 2) Study the selection regimes that maintain the inversions across a gradient of sea water temperate using population genomics; 3) Pinpoint the genes and regulatory elements within the inversions that are involved in adaptation to sea water temperature using gene expression and functional genomics.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Large chromosomal inversions have been increasingly linked to local adaptation in natural populations. Despite their importance, there is current debate about what evolutionary forces maintain inversion polymorphisms in natural populations, particularly regarding the interplay between balancing and divergent selection. Furthermore, limitations of sequencing technologies often result in poor characterization of inversion breakpoints obscuring our understanding of their functional impact. INVERT2ADAPT will focus on Atlantic herring (Clupea harengus) as a model system to study the contribution of chromosomal inversions to local adaptation using multiple genomics tools. First, I will characterize the chromosomal inversions and date their origin relatively to the evolutionary history of Atlantic herring using comparative genomics and phylogenomics. Second, I will study the selection regimes that maintain the inversions across a gradient of sea water temperate using population genomics. Lastly, I will pinpoint the genes and regulatory elements within the inversions that are involved in adaptation to sea water temperature using gene expression and functional genomics. The project will allow to better understand how Atlantic herring is able to survive across a wide range of sea water temperature in the Atlantic Ocean. A clear establishment of the link between linking genotype, phenotype and environment is important to understand how Atlantic herring might adapt to changes in sea water temperature induced by global warming. INVERT2ADAPT will also contribute to a better understanding of how structural variation, including large chromosomal inversions, contribute to adaptation in natural populations. The project will be implemented in Uppsala University under the supervision of Professor Leif Andersson.

Оригинален текст от CORDIS (на английски).

Участници

  • UPPSALA UNIVERSITET · UppsalaКоординаторШвеция

Връзки

Данни: CORDIS, © Европейски съюз