HEИндивидуална стипендия2022–2024

SENSINGTech · Sensor-based technological platform to investigate the effect of age-induced changes of oral physiology on the bolus properties and on the subsequent phases of swallowing and digestion

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период: 2022-09-01 → 2024-08-31
Финансиране от ЕС: 195 915 €
Участници: 1
Схема: HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Промените в устата при стареенето влияят върху това как храната се сдъвква и гълта. Разбирането на тези процеси помага да се определят безопасните характеристики на храната за хора с затруднено гълтане.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Sensor-based technological platform to investigate the effect of age-induced changes of oral physiology on the bolus properties and on the subsequent phases of swallowing and digestion

SENSINGTech is an interdisciplinary research project that leverages a comprehensive sensor- based platform to study the evolution of food properties in the mouth and the dynamics of oral processing, including the role of saliva in the proccess of food bolus formation. The project aims to quantify the impact of impaired oral conditions on swallowing and digestion. To address the challenges of studying food ingestion in vulnerable populations, SENSINGTech will develop a quantitative in vitro model that mimics the human feeding process, including the “Stage II Transport” of solid foods — a critical aspect not yet replicated by any existing in vitro systems. The objectives of SENSINGTech are to: - integrate in vitro mastication and swallowing technologies to replicate the complex dynamics of “Stage II Transport” during solid food intake - investigate the influence of masticatory parameters, saliva addition, and its distribution on bolus properties, and their impact on subsequent swallowing and digestion phases - provide critical insights to define clear thresholds for food characteristics that ensure safe swallowing, tailored to the severity and specific areas affected by swallowing disorders.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The main goal of oral processing is preparing food for swallowing and digestion, where mastication determines the effective surface area of food particles and food bolus properties. Ageing induces changes in oral physiology leading to substantial alterations in bolus properties, bioaccessibility, and bioavailability of nutrients. The impact of age-related alterations on swallowing and digestion can be intensified by health conditions that may cause dysphagia. SENSINGTech is an interdisciplinary research project that, integrating a full sensor-based technological platform, aims to investigate the evolution of food properties in mouth, and the dynamics of food oral processing and saliva addition on bolus formation, to quantify its impact on both swallowing and the delivery of nutrients. This work aims to provide clear-cut boundaries of food characteristics that ensure a safe swallow. The key limitation of working with vulnerable people to accurately measure mastication, swallowing and digestion will be overcome by developing a quantitative in vitro approach that mimics the human feeding process, monitoring the “Stage II of transport” for solid food intake – not captured by any in vitro system yet. This project will enable the fellow to acquire a strong competence in food oral processing, swallowing, and digestion, learning new methodologies and applications to meet the challenges linked to population ageing and the management of dysphagia. This research will address the Horizon Europe (HE) efforts devoted to “Health”, where the unique combination of expertise will lead the candidate towards an independent scientist career of high quality and strong international visibility. SENSINGTech will therefore be a milestone for the future research career of the applicant, positioning both the fellow and the host in leading positions in food oral processing and the dysphagia research field.

Оригинален текст от CORDIS (на английски).

Участници

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT · ParisКоординаторФранция