HEИндивидуална стипендия2022–2024

EMOFFF · Edible Metal-Organic Frameworks for Food Fortification

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период: 2022-08-01 → 2024-08-31
Финансиране от ЕС: 187 624 €
Участници: 3
Схема: HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Ядливи метал-органични рамки се разработват за добавяне на микроелементи, като например желязо, в хранителните продукти. Това помага за справяне с недостига на важни вещества в организма, който води до анемия и проблеми с развитието.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Edible Metal-Organic Frameworks for Food Fortification

The primary objective of the EMOFFF project is to develop innovative, edible metal-organic frameworks (MOFs) that can be used to fortify food products with essential micronutrients, such as iron. The project aims to create MOFs that are not only effective in delivering these nutrients but also safe for consumption and capable of maintaining their stability and bioavailability in various food matrices. The project is motivated by the pressing need to find sustainable and effective solutions to combat micronutrient deficiencies, which have severe health implications, including anemia, impaired cognitive development, and increased susceptibility to infections. Traditional methods of food fortification often face challenges such as poor bioavailability, undesirable taste, and stability issues. EMOFFF seeks to overcome these challenges by leveraging the unique properties of MOFs.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Insufficient intake of iron is one of the most common micronutrient deficiencies, with almost one-third of reproductive-aged women suffering from anaemia. Iron fortification of food products is an important route towards addressing this issue, but it is a notoriously difficult problem as product quality is often strongly compromised. While current strategies succeed in addressing some aspects of this challenge, they are often inadequate from a holistic perspective. Resolving these issues will help address societal challenges related to iron deficiencies, provide personalised nutrition, and support the growing adoption of plant-based diets. The objective of this research program is to explore the novel approach based on functional materials from metal-organic frameworks (MOFs) derived from iron (Fe) and edible plant-derived organic molecules, which can function as safe and bioaccessible by-design colloidal delivery systems. The approach will be based on selecting suitable organic ligands from the family of edible, plant-based polyphenols and acids, and use them in safe concentrations as Fe-based MOFs with pH triggered solubility (i.e. reversal back to the mineral and organic ligand) in the gastrointestinal tract. To achieve this goal, the following specific objectives will be met by developing new edible MOFs, both homogeneous and core-shell morphology, from Fe and plant-derived polyphenols and acids and evaluating their reactivity (e.g. oxidation, discoloration) and bioaccessibility in food products. If successful, this approach will enable the design of high-quality, mineral-enriched, plant-based food products. The proposed research program will lead to an increase in high-impact Research & Innovation output in the field of nutritious and functional food, specifically addressing the issue of iron deficiency. The expanded skill set of the fellow will improve his future employability and career prospects, both in industrial and academic research areas.

Оригинален текст от CORDIS (на английски).

Участници

UNILEVER INNOVATION CENTRE WAGENINGEN BV · WageningenКоординаторНидерландия
UNIVERSITEIT UTRECHT · UtrechtНидерландия
WAGENINGEN UNIVERSITY · WageningenНидерландия