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HEОбмен на изследователи2023–2027

ARGO · Towards development of new antibacterial strategy for dentistry

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период
2023-03-01 → 2027-02-28
Финансиране от ЕС
915 400 €
Участници
6
Схема
HORIZON-TMA-MSCA-SE

Линиите свързват координатора с партньорите.

Накратко на български

Наночастици от сребро и мед се интегрират в биоактивни материали за лечение на зъбни инфекции и рани. Това помага за намаляване на зависимостта от антибиотици и подобрява възстановяването на тъканите.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Towards development of new antibacterial strategy for dentistry

Dental infections, including root canal infections and post-surgical complications, frequently require antibiotic treatment, contributing to the rise of antibiotic-resistant bacteria. The ARGO consortium aims to reduce antibiotic dependency by integrating silver (AgNPs) and copper nanoparticles (CuNPs) into hydroxyapatite (HA) composites and electrospun nanofiber membranes. These bioactive materials offer localized antimicrobial effects, reducing infection risks and improving treatment outcomes in dentistry and wound healing. Furthermore, existing dental materials often lack biocompatibility, durability, and regenerative potential. The ARGO project is pioneering nanostructured materials that not only fight infections but also support tissue regeneration, thereby offering a more sustainable, long-term solution for dental care. By developing next-generation antimicrobial materials, ARGO seeks to: - Reduce the need for antibiotics in dental care, addressing the global antimicrobial resistance crisis. - Enhance patient safety and recovery by introducing biocompatible, infection-resistant biomaterials. - Bridge the gap between research and clinical practice, facilitating the adoption of nanotechnology-based materials in real-world dentistry and wound healing applications. - Boost international scientific collaboration, ensuring knowledge exchange across multiple disciplines, including materials science, microbiology, and clinical dentistry.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

ARGO project will be dedicated to explore innovative activities with focus on strong international, interdisciplinary and inter-sectoral cooperation in fields of chemistry, biomaterials, nanotechnology, microbiology, cell biology and dentistry. ARGO network will involve academic and industrial partners from EU MS and associated countries with the aim to open potential for innovative solutions in nanomaterials and clinical dentistry. The primary research goal of the project is to facilitate R&I activities with complementary competences of participant organizations for development of new antibacterial materials for dentistry, particular for the development a new antibacterial root-filling material.The project will be realized through the tight cooperation between partner organizations to create synergies for development and testing of innovative biomaterials for dentistry. The innovative technologies will be used to produce a root-filling material with nanoparticles with tailored biological and antibacterial properties. Evaluation of a new biomaterials with silver nanoparticles in vitro will be carried out on a specially designed tooth model. Biocompatibility and in-vivo assessment will be used to prove antibacterial effect of the new biomaterial on a relevant animal model. Interdisciplinary and inter-sectoral secondment will be the main tool for project realization with aim of strengthening research, training, communication and networking capacities of participant organizations and knowledge transfer from academia to industry and vice versa. Proposed research and training goals will lead to increased research, transferable skills and competences of early stage researcher with the aim to improve employability and career perspectives in both academic and industrial sectors. Public dissemination of new research results will increase the awareness in the general society of the role of research and researchers in development of EU as a leading destination for R&I.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз