HEИндивидуална стипендия2023–2025

MINIMA · Microbial navigation strategies in ecologically relevant porous media

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период
2023-08-01 → 2025-07-31
Финансиране от ЕС
191 760 €
Участници
2
Схема
HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Микроорганизмите и техните стратегии за движение в тесни, порести пространства, като например в почвата, са в центъра на вниманието. Разбирането на тези процеси помага да се разбере как бактериите оцеляват, разпространяват се и поддържат околната среда.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Microbial navigation strategies in ecologically relevant porous media

Microorganisms may be too small to see, but they are everywhere around us—and inside us. In fact, the number of bacteria living in our body is roughly the same as the number of human cells we have. These tiny companions keep us healthy by aiding digestion, defending against harmful germs, and even shaping how we feel. Just as importantly, microorganisms sustain the environment by recycling nutrients, enriching soil, and purifying air and water. They make life possible on both our bodies and our planet. Most microorganisms live in tiny porous spaces, much like we live in houses or shelters. These pores give them protection from predators and help keep their surroundings stable and comfortable. At the same time, living in such tight spaces also brings challenges: limited room to grow, slower access to nutrients, restricted movement, and even physical pressure from the surrounding walls. Yet microorganisms find ways not just to survive, but also to spread and flourish in these confined spaces. The clever strategies they use remain a source of fascination and inspiration for scientists. But many of these strategies are still a mystery. How do such small organisms overcome the physical limits of the environments they inhabit? What rules guide their movements and choices when the landscape becomes complex? Our project, MINIMA (“Microbial navigation strategies in ecologically relevant porous media”), takes on these questions. We want to know: How do the sizes of pores, compared to the size of the microbes themselves, affect their ability to move efficiently? What do microorganiams do—both in their behavior and in their biology—when they face difficulties such as tight spaces or rough surfaces? And can the very structure of these porous spaces decide whether microbes keep swimming freely or settle down to form communities? Beyond curiosity, this project also has real-world impact: it can help us better understand how soil helps regulate carbon in nature, how underground spaces might be used for clean energy storage, and even inspire new biomedical microrobots that navigate the human body.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The navigation of microorganisms in porous environments has received much research attention not only because of its relevance to many ecological, medical, and technological situations, from soil bioremediation to pathogenesis, but also as a representative problem in the recently emerging field of active matter. Taking soil as an example, such a hierarchical complex porous structure presents multiple challenges to navigating microorganisms, but we still lack a comprehensive mechanistic model that could solve the active navigation problem of microorganisms in such environments. In this project, I aim to uncover navigation strategies of microorganisms in features of different length scales, focusing on their swimming in porous structures and sliding on rough surfaces. Leveraging a cross-disciplinary approach by combining microfluidics, advanced optical microscopy, computer-assisted image analysis, and numerical modeling, I expect to extract a general criterion for the optimal spreading by microorganisms in porous media, and to discover underlying microbial feedback mechanisms in relation to their porous environments. The results of the proposed research will be of interest not only to the fundamental physics of ""active matter under confinement"", but also of practical relevance to soil bioremediation, biomedical micromotor and antimicrobial surfaces development. This project will provide a solid opportunity to build my multi-disciplinary research profile and experimental skills, ultimately bringing me significantly closer to my career aspirations of being an internationally visible independent researcher.""

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз