HEИндивидуална стипендия2024–2026

ONGUARD · Study on the influence of nitroxyl (HNO) and nitric oxide (NO) bioactivity on potato defense against pathogens: on the lookout for improving the global food supply.

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период: 2024-02-01 → 2026-01-31
Финансиране от ЕС: 155 794 €
Участници: 2
Схема: HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Молекулите азотен оксид и нитроксил регулират защитата на картофите срещу патогени, като например гъбичката, причиняваща мана. Разбирането на тези химични сигнали помага за подобряване на устойчивостта на растенията и осигуряването на хранителните ресурси в света.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Study on the influence of nitroxyl (HNO) and nitric oxide (NO) bioactivity on potato defense against pathogens: on the lookout for improving the global food supply.

Plants face many environmental and biological threats that can damage their growth and productivity. In response, they activate protective systems based on signaling molecules like nitric oxide (NO), which help coordinate defense responses. Recently, a closely related molecule, nitroxyl (HNO), was detected in plants for the first time. Although HNO has been studied in medicine, its role in plant biology remains unknown. This project explored whether plants naturally produce HNO during a pathogen attack and whether this molecule plays a role in regulating plant immunity. We developed a method to detect HNO in real time in potato leaves infected with a fungal-like pathogen that causes late blight, a devastating crop disease. Our findings showed that HNO levels increased during infection and were influenced by the plant's redox balance (its ability to control oxidation). We also found that applying HNO externally could reduce disease symptoms, suggesting it has a protective role. The project helps explain how plants coordinate internal chemical signals when attacked by pathogens.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Potato (Solanum tuberosum L.) is one of the world’s most important crops for human consumption, thus it is an integral part of the world's food supply. Poland is the world's 8th largest producer (2nd in the EU), with 9 million tons annually. Potato is susceptible to a wide range of pathogenic organisms, which can cause severe quality and yield losses worldwide. Given the absence of cultivars resistant to pathogens and the immunization of pathogen isolates to successive fungicides, any attempt to understand and strengthen the knowledge of factors related to natural potato immunity is extremely important.In light of this, it is well documented that nitric oxide (•NO) is a key element involved in pathogen recognition as well as activation of local and systemic plant defense signaling activities and pathways. Moreover, the interdisciplinary group proposing this plan recently reported endogenous production of HNO (nitroxyl) in plant tissues (Arabidopsis thaliana) for the first time, and points toward a novel regulatory role. Under physiological conditions, HNO concentration in plant cells is in the nanomolar range. The ubiquitous HNO bioavailability allows it to support or compete with •NO signaling, depending on the local redox environment (shifts with stress or senescence). Finally, we showed that HNO formation is an early reductive stress-related response.Taking all this into account, this proposal will focus on the real-time detection and visualization of simultaneously endogenous HNO and NO in leaves of the important crop plant challenge inoculated with vr/avr Phytophthora infestans, a cause of late blight disease. Moreover, it will be an important issue to answer the question of whether and to what degree the HNO presence in cells modifies the plant's defense responses. The hypothesis is that HNO is generated during potato - P. infestans interaction and can act as a functional signal molecule favoring redox changes towards effective defense responses in potato.

Оригинален текст от CORDIS (на английски).

Участници

UNIWERSYTET IM. ADAMA MICKIEWICZA WPOZNANIU · PoznanКоординаторПолша
POLITECHNIKA POZNANSKA · POZNANПолша