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HEОбмен на изследователи2023–2027

ESCULAPE · Electro-conductive polymeric 3D scaffolds as novel strategies for biomedical applications

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период
2023-11-01 → 2027-10-31
Финансиране от ЕС
1 444 400 €
Участници
13
Схема
HORIZON-TMA-MSCA-SE

Линиите свързват координатора с партньорите.

Накратко на български

Електропроводни полимерни 3D структури се разработват за възстановяване на тъкани, например при сърдечно-съдови или костни увреждания. Тези материали помагат за по-доброто интегриране на имплантите в тялото и по-лесното проследяване на възстановяването на пациента.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Electro-conductive polymeric 3D scaffolds as novel strategies for biomedical applications

ESCULAPE project addresses the urgent need for advanced, sustainable, and clinically relevant biomaterials to support regenerative medicine, with a focus on cardiovascular and musculoskeletal applications. Existing solutions often fall short in long-term biocompatibility, mechanical performance, or integration with host tissues. Europe also faces strategic pressure to accelerate the translation of innovative materials into clinical practice while ensuring patient safety, ethical compliance, and socio-economic relevance. ESCULAPE aims to develop next-generation electroconductive polymeric 3D scaffolds capable of supporting tissue regeneration, integrating with host tissues, and enabling biological monitoring. The project combines expertise in materials science, biomedical engineering, and clinical sciences to ensure that innovations are both technologically advanced and clinically meaningful. ESCULAPE will deliver high-performance biomaterials, scalable fabrication methods, and advanced characterization data to enable preclinical evaluation and future clinical applications. These outcomes contribute to EU priorities in regenerative medicine by improving therapeutic performance, reducing healthcare burdens, and enhancing Europe’s leadership in advanced biomaterials. Social sciences and humanities inform ethical frameworks, patient-centred design, and pathways for responsible technology adoption. Expected impacts include improved regenerative implant performance, enhanced monitoring of tissue recovery, and long-term potential to address chronic conditions affecting millions of patients across Europe.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

ESCULAPE project is targeted to building a strong interdisciplinary partnership in order to support joint research and innovative activities in the fields of biomaterials, polymer science, nanotechnology, tissue engineering, microbiology and medicine with the aim to explore development and implementation of new medical engineering solutions for regenerative medicine and wearable electronics.The project will offer novel solutions (from the manufacturing stage to exploitation strategies) using MXenes, a new class of two dimensional (2D) materials consisting of transition metal carbides/carbonitrides. MXenes will be employed to modify properties and qualities of porous 3D electrospun nanoscaffolds, which will be used in tissue engineering for regenerative biomedicine and development of wearable electronics on both woven and non-woven fabrics.The main goal of the ESCULAPE project is to build a new training partnership to develop innovative strategies to achieve advanced biomaterials with target-oriented properties (electrical conductivity, biocompatibility etc.) that will be able to deliver specific features for regeneration of heart and nerve tissues, regulation of homeostasis in iPSCs, as well as in development of wearable electronics.Interdisciplinary and inter-sectoral secondments will be the main tool for project realization with the aim of strengthening research, training, communication and networking capacities of participant organizations and knowledge transfer from academia to industry and vice versa. Proposed research and training goals will lead to enhance research and transferable skills of the ESRs, as well as their competences with the aim of improving competitive employability and career prospects in both academic and industrial sectors. Public dissemination of new research results will increase the awareness of general society on the role of researchers and research infrastructure in establishing the EU as a world leading R&I force.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз