HEИндивидуална стипендия2024–2026

NanoTrojans · Development of Mass Spectrometry based Analytical Methods for High-throughput Nanoplastic Screening in Environmental and Biological Systems

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период: 2024-10-01 → 2026-09-30
Финансиране от ЕС: 169 327 €
Участници: 2
Схема: HORIZON-TMA-MSCA-PF-EF

Линиите свързват координатора с партньорите.

Накратко на български

Нанопластмасите в храната, природата и живите организми се анализират чрез нови методи за определяне на размера и количеството им. Това помага за по-точното проследяване на микроскопичните частици и прикрепените към тях метални примеси.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Development of Mass Spectrometry based Analytical Methods for High-throughput Nanoplastic Screening in Environmental and Biological Systems

The main research and innovation objective of this project is the development, validation and application of novel analytical methods that aim to overcome current shortcomings in the detection and quantitation of nanoplastics, in environmental, food and biological systems. This includes the routine, high throughput, screening analysis of nPLs (1-1000 nm) in environmental and food samples. The analytical chemistry methods proposed in the NanoTrojans project aim to provide capabilities that can be used to determine nPL particle size and the polymer or carbon (C) amount per particle size fraction. These two parameters can be used to estimate nanoplastic particle number concentrations, providing the plastic’s density is known. The proposed methods will also be used to monitor the presence of metal(-loid)s either as additives or adsorbed on nanoplastic surfaces.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Nanoplastics (nPLs), defined as organic polymeric particles ranging in size from 1–1000 nm, represent emerging contaminants that are of significant relevance to environmental and food science, especially since initial toxicological studies have shown them to cross the gut barrier with unpredictable long-term effects. Such early-stage research signifies the need to study nPL behavior in greater detail, both in terms of their physicochemical behavior in the environment, as well as their toxicity. The latter may also be affected by their potential to (ad)sorb and transport other chemicals, especially toxic metals and organic pollutants, into living systems. Compared to microplastics (μPLs) ranging in size from 1-5 mm, nPLs possess significantly larger surface-to-volume ratios, thus making this effect more pronounced. As a result, such a Trojan horse-like transport of toxic chemicals into cells urgently needs further study and improved understanding. Therefore the main research and innovation objective of this project is the development, validation and application of novel analytical methods that aim to overcome current shortcomings in the detection and quantitation of nPLs, in environmental, food and biological systems. The analytical methods proposed in this project (hydrodynamic chromatography on-line with inductively coupled plasma mass spectrometry along with appropriate sample preparation procedures) aim to provide capabilities that can be used to determine nPL particle size and the polymer or carbon amount per size fraction. These two parameters can be used to indirectly estimate nPL particle number concentrations, providing the plastic’s density is known. The proposed methods will also be used to monitor the presence of metals or metalloids either as additives or adsorbed onto nPL surfaces.

Оригинален текст от CORDIS (на английски).

Участници

PANEPISTIMIO KRITIS · RETHIMNOКоординаторГърция
HELLENIC CENTRE FOR MARINE RESEARCH · Attikia AnavissosГърция