TB-SPECTRUM · A step forward for unraveling the immune mechanisms and tools for tuberculosis spectrum management
„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“
- Период
- 2026-01-01 → 2029-12-31
- Финансиране от ЕС
- 896 790 €
- Участници
- 9
- Схема
- HORIZON-TMA-MSCA-SE
Линиите свързват координатора с партньорите.
Накратко на български
Имунните механизми при туберкулоза се изследват, за да се разбере как тялото реагира на инфекцията в различните ѝ фази. Това помага за откриване на биомаркери, които да идентифицират хора с висок риск от развитие на болестта или скрити форми на инфекцията.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Цел на проекта
TB-SPECTRUM aims to strengthen international research collaboration among different sectors and disciplines, and to structure a network to perform high-quality, translational, and multidisciplinary research for (i) a better understanding of tuberculosis (TB) spectrum immune mechanisms; and (ii) increasing the capacities of the involved staff fostering training and networking activities, as well as increasing their inter-sectoral employability opportunities. Understanding the host-pathogen interactions in the different phases of the spectrum is fundamental for detecting biomarkers of disease progression that can lead to new diagnostic approaches for identifying those individuals with a high-risk of developing disease if infected or for detecting subclinical TB forms. However, it is still unknown which immunological mechanisms are involved in infection/disease progression. To unravel this knowledge gap, it is mandatory to develop collaborative research which combines different expertise in the TB field (clinics, diagnostics, treatment, clinical studies management, cellular/humoral immunology, genomics, and technology transfer, among others). For that purpose, a Consortium of nine academic and non-academic Institutions harboring TB-renowned experts has been constituted. This network is formed by specialists in the clinical management of active TB cases and their contacts (from high and low incident countries); experts in basic/applied science; and a small and medium-sized enterprise (SME) involved in the development of immune assays. Altogether, the proposed goals will be achieved through secondments among the different sectors, which will be extremely important for progressing to a better understanding of the requirements needed in TB management and control; and will expose participants to new research environments that will reinforce multidisciplinarity. Moreover, the interaction with an SME will improve knowledge transference skills, stimulating entrepreneurship.
Оригинален текст от CORDIS (на английски).
Участници
- INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL · Badalona BarcelonaКоординаторИспания
- ACADEMISCH ZIEKENHUIS LEIDEN · LeidenНидерландия
- BINGHAM UNIVERSITY · KARUНигерия
- Genome Identification Diagnostics GmbH · StrassbergГермания
- I3S - INSTITUTO DE INVESTIGACAO E INOVACAO EM SAUDE DA UNIVERSIDADE DO PORTO · PortoПортугалия
- INSTITUTIA MEDICO-SANITARA PUBLICA - INSTITUTUL DE PNEUMOLOGIE ""CHIRIL DRAGANIUC"""" · CHISINAUМолдова
- INSTITUTUL DE PNEUMOFTIZIOLOGIE MARIUS NASTA · BucurestiРумъния
- SERVICIOS CLINICOS SA · BarcelonaИспания
- THE UNIVERSITY OF TEXAS SYSTEM · AustinСъединени щати
Връзки
Данни: CORDIS, © Европейски съюз
