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HEДокторантска мрежа2027–2030

AstroCirc · ASTROcytes in CIRCuits: Unraveling their contribution in healthy and diseased brain circuits.

„Хоризонт Европа“ — Действия „Мария Склодовска-Кюри“

Период
2027-01-01 → 2030-12-31
Финансиране от ЕС
4 527 606 €
Участници
27
Схема
HORIZON-TMA-MSCA-DN

Линиите свързват координатора с партньорите.

Накратко на български

Астроцитите и тяхното взаимодействие с невроните се изследват, за да се разбере как тези клетки влияят върху работата на мозъчните вериги. Това е важно, за да се открият нови механизми на развитие и начини за терапия при неврологични заболявания.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Цел на проекта

In 2021, an estimated 3.4 billion people—about 43% of the world’s population—were living with a neurological condition, underscoring the need for new strategies to understand and treat brain disorders. Decades of predominantly neuron-centric research have not delivered the breakthroughs required to reduce their growing global burden.AstroCirc proposes a shift toward a more complete view of brain circuitry by integrating the roles of astrocytes—the most abundant non-neuronal cells, essential for brain homeostasis and circuit dynamics. By leveraging astrocyte function, AstroCirc aims to uncover novel disease mechanisms and develop astrocyte-based, disease-modifying therapeutic strategies, expanding the options available to tackle neurological diseases.AstroCirc will train 15 doctoral candidates (DCs) in astrocyte–neuron interactions and neural circuitry, building on the project’s cross-disciplinary and intersectoral framework. DCs will be mentored by leading experts in glial biology and will access advanced methodologies and unique model systems across the consortium.Their research will span multiple levels of brain organization: from synaptic function as the basic unit of circuits (WP1), to circuit integration within brain networks (WP2), and finally to the development of astrocyte-informed interventions for a broad variety of neurological, neuropsychiatric, and neurodegenerative disorders (WP3).AstroCirc’s impact will be reflected in DCs equipped with strong technical and transferable skills, positioning them for successful careers beyond the project. Ultimately, AstroCirc will foster a new generation of researchers who drive and advocate for glia-centered approaches within European research and innovation.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз