Exercice in the heat how can the life threatening combination of hyperthermia and dehydration be overcome
4РП — Обучение и мобилност на изследователи
- Период
- 1996-07-01 → 1998-06-30
- Финансиране от ЕС
- —
- Участници
- 2
- Схема
- RGI
Линиите свързват координатора с партньорите. За проекти отпреди 2014 г. CORDIS не винаги дава точни координати. Тези точки са на ниво град или държава.
Накратко на български
Физиологичните механизми при работа на горещо изследват как обезводняването и високата температура влияят върху сърдечния дебит и кръвоснабдяването на мускулите и кожата. Това помага да се разбере защо се стига до опасно за живота топлинен удар при тежък физически труд.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Цел на проекта
During prolonged heavy physical work at high environmental temperatures people are at high risk of suffering from heat exhaustion and life-threatening heat stroke. This might be the case for many people engaged in physical work or recreational and competitive sports in the Southern European Countries during the hot Summers during which ambient temperature may surpass 400C. Prolonged intense physical work in the heat might lead to heat exhaustion and heat stroke as a results of the progressive impairment of cardiovascular, metabolic and thermoregulatory functions accompanying the concomitant losses in body water throughout sweating (i.e., dehydration). More specifically, heat exhaustion during physical work at high environmental temperature might be the end-result of the integrated effect of progressive increases core temperature (i.e., hyperthermia) and progressive reductions in cardiac output and mean arterial pressure with dehydration. Significant reductions in cardiac output might lead to significant alterations in metabolism and heat dissipation due to possible concurrent reductions in contracting muscle blood flow, splanchnic blood flow and skin blood flow. The purpose of this investigation is to determine the physiological mechanisms underlying reductions in cardiac output and the possible concomitant decline in blood flow to active muscles, splanchnic tissue and skin vasculature with dehydration during physical work in a hot environment in humans. The specific aims of this investigation are to: 1) determine whether the significant reductions in cardiac output with exercise-induced dehydration are accompanied by significant declines in exercising muscle blood flow, splanchnic blood flow and skin blood flow, 2) determine whether reductions in cardiac output with exercise-induced dehydration are accompanied by increases in muscle glycogen utilisation and muscle lactate production, 3) determine whether the increases in muscle, splanchnic and cutaneous vascular resistance during physical work in the heat are associated with an increased sympathetic outflow, 4) determine to what extent the reductions in cardiac output with exercise-induced dehydration due to the declines in stroke volume and central venous pressure are prevented by hypervolemia.
Оригинален текст от CORDIS (на английски).
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Данни: CORDIS, © Европейски съюз