THE CENTRAL ROLE of THE UBIQUITIN PROTEASOME SYSTEM IN REGULATORY PROCESSES INVOLVED in IMMUNOLOGICAL, INFLAMMATORY, ENDOCRINOLOGICAL AND MALIGNANT DISORDERS
4РП — Обучение и мобилност на изследователи
- Период
- 1996-10-01 → 2001-09-30
- Финансиране от ЕС
- —
- Участници
- 5
- Схема
- NET
Линиите свързват координатора с партньорите.
Накратко на български
Убиквитин-протеазомната система контролира разграждането на протеини в клетките, което влияе върху процеси като клетъчния цикъл и презентацията на антигени. Разбирането на този механизъм помага при търсенето на нови цели за разработване на лекарства в медицината и фармацията.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Цел на проекта
The ubiquitin pathway plays a major role in regulated degradation of cellular proteins. It is involved in basic processes such as cell cycle educated scientists. During the four years of training, a comprehensive education will be provided via a three-stage program: the Network will hire regulation, tumour suppression, antigen presentation, regulation of young scientists immediately after their Ph.D. for a period of two years, apoptosis, and modulation of signal transduction. they will receive state-of the-art training in a research project using The objectives of the proposed project are to further elucidate the advanced facilities. Thereafter, they will be working in cooperative ubiquitin proteasome protein degradation system and to dissect the role of research projects (between partners). In total, six to ten post-doctoral the system in antigen presentation, regulation of cell cycle and degradation of growth and transcriptional regulators. Subsequently, it fellows will be educated. will be possible to identify potential targets for designed drug development in biomedicine and pharmaceutics. | The proposed Network brings together prominent European researchers in the field and will become a platform of international standard. Together the partners have at their disposal all modern facilities required for advanced biomedical research. Its composition and stature guarantees pioneering and innovative breakthroughs in the future. True collaboration and technology transfer are essential for their success.
Оригинален текст от CORDIS (на английски).
Участници
- Rijksuniversiteit Utrecht · UtrechtКоординаторНидерландия
- INSTITUT PASTEUR · PARISФранция
- KAROLINSKA INSTITUTE · STOCKHOLMШвеция
- RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG · HEIDELBERGГермания
- Universität Stuttgart · StuttgartГермания
Връзки
Данни: CORDIS, © Европейски съюз