STUDY OF MULTINUCLEAR COPPER AND ZINC COMPLEXES RELEVANT TO BIOLOGICAL ELECTRON TRANSFER PROCESSES AND SUBSTRATE BINDING

Линиите свързват координатора с партньорите.

Накратко на български

Цел на проекта

Research objectives and content we plan to design novel oligopyridine ligands for the self assembly of (supra-)molecular structures as models for oligometal enzymes. Rigid, linear polytopic ligands containing bidentate chelating sites will be used to self-assemble into square matrix arrays of metal centers with ions of tetrahedral coordination geometry, Zn(II) and Cu(I). By varying the number of coordination sites on the ligands, different sizes and shapes of metal arrays are envisioned. Additional ligands could be introduced by tuning solvation and anion interactions. This new approach to model the active sites of polynuclear metallo enzymes has the potential to yield large electron reservoirs to serve as relays in multi-electronic reduction processes (Cu) and provide complexes with the enhanced reactivity and selectivity of multi- metal hydrolytic enzymes (Zn). Training content (objective, benefit and expected impact) Through this project, the applicant will learn new synthetic methods of the preparation of self-assembly systems, as well as state-of-the-art spectroscopic techniques needed for sophisticated polyelectronic systems. This work is anticipated to result in biomimetic transformations which are of high interest in the fields of pharmacological and environmental chemistry. Links with industry / industrial relevance (22) Complexes might be used to investigate oxygenation reactions which are relevant to the development of practical catalysts for the mild, selective oxidation of organics. This project will be carried out on a non-financial basis, with potential interest of Rhtne-Poulenc.

Оригинален текст от CORDIS (на английски).

Участници

• UNIVERSITE LOUIS PASTEUR, STRASBOURG 1 · STRASBOURGКоординаторФранция

Връзки

• Виж в CORDIS