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FP6Докторантска мрежа2004–2008

EURO-RA · Functional Genomic Approaches Targeting Arthritis

6РП — Действия „Мария Кюри“

Период
2004-10-01 → 2008-09-30
Финансиране от ЕС
3 580 223 €
Участници
11
Схема
RTN

Линиите свързват координатора с партньорите. За проекти отпреди 2014 г. CORDIS не винаги дава точни координати. Тези точки са на ниво град или държава.

Накратко на български

Генетичните механизми на ревматоидния артрит се анализират чрез методи като протеомния анализ и биоинформатиката. Това помага за разбирането на развитието на заболяването и създаването на по-ефективни методи за терапия.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Final Activity Report Summary - EURO-RA (Functional Genomic Approaches Targeting Arthritis)

The Marie Curie research training network, EURO-RA, brought together leading groups in the field of rheumatoid arthritis research in Europe. Rheumatoid arthritis is a systemic, inflammatory, progressive, chronic and destructive disease affecting primarily peripheral joints, which is associated with pain, disfigurement and various systemic manifestations. It is the most common chronic inflammatory autoimmune disease affecting Europeans. The primary goal of the network was to offer to young researchers the opportunity to participate in a state of the art multidisciplinary training in functional genomics' approaches studying arthritis. This goal was achieved and the network trained 32 fellows during four years. On the other hand, the main scientific goal was to capitalise on the modern post-genome methodologies, such as genome wide expression profiling, proteome analysis, bioinformatics, comparative genomics and mutagenesis, to study rheumatoid arthritis. This combined effort of 12 research groups from nine European countries aimed to identify susceptibility genes that determined the onset, progression and chronicity of autoimmune arthritis. This in turn would provide an excellent opportunity to improve our knowledge on the in vivo disease mechanism and, hence, to develop more rational forms of therapy. The network made considerable progress in that direction. Network scientists published articles in leading scientific journals on those topics and filed patents on experimental therapies for rheumatoid arthritis.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The Research Training Network, EURO-RA, brings together leading groups in the field of Arthritis research in Europe. The Network primary aim is to offer training on functional genomics methodologies to early stage and experienced researchers. The Network additional aim is fostering the transfer of knowledge between the participating European laboratories. The network will achieve these aims through collaborative research projects and transfer of knowledge tools such as workshops, courses, meetings and secondements. The main scientific goal is to capitalize on the modern postgenome methodologies such as genome-wide expression profiling, proteome analysis, comparative genomics , and genome-wide mutagenesis and linkage analysis to study Rheumatoid Arthritis. Rheumatoid Arthritis is the most common chronic inflammatory autoimmune disease affecting the European population.It is a systemic, inflammatory, progressive, chronic destructive disease affecting primarily peripheral joints, that is associated with pain, disfigurement, and various extraarticular manifestations. This combined effort of 12 research groups from 9 European countries aims to identify genes that determine the onset, progression and chronicity of autoimmune arthritis. This in turn will provide an excellent opportunity to improve our knowledge on in vivo disease mechanism and, hence, to develop more rational forms of therapy. The Network primary aim is to offer training on functional genomics methodologies as applied to autoimmune research to early stage researchers and to and foster transfer of knowledge between the participating European institutes.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз