BIONEL · Bioanalytical electrochemistry and bionanotechnology BIONEL""
6РП — Действия „Мария Кюри“
- Период
- 2005-01-01 → 2008-12-31
- Финансиране от ЕС
- 1 185 831 €
- Участници
- 1
- Схема
- EST
Линиите свързват координатора с партньорите.
Накратко на български
Биоаналитичната електрохимия изследва процеси в живи клетки, като например преноса на електрони при бактерии или работата на неврони. Тези проучвания помагат за по-доброто разбиране на клетъчните мембрани и стабилизирането на клетки чрез полимери.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Final Activity Report Summary - BIONEL (Bioanalytical electrochemistry and bionanotechnology)
In this project, five PhD students have been trained for three years each and by the end of this project they have all started to finalise their doctoral theses. The PhD students have been financed by the project for three years and by various research grants / faculty for an additional year (according to the Swedish system for which a PhD takes net four years). About half their time they have been taking advanced courses and half time they have been devoted to experimental research, publishing, scientific conferences, etc. They have all published a number of scientific articles in peer reviewed international periodicals (which is a requirement in Sweden to get a PhD). They have also been active in teaching undergraduates. This Early Stage Training Site was divided into five main subprojects and in each subproject one PhD student was recruited. The subprojects were as follows: Project 1) Amperometric- and impedance measurements on eukaryotic cells (yeast and mammalian cells). PhD student: Natalie Kostesha (female, Russia). nine-months fellows: Zdenka Fohlerova (female, Slovakia, and Nicholas Haslett (male, New Zealand). Project 2) Electron transfer mechanisms at cell membranes and / or living prokaryotic cells (bacteria). PhD student: Vasile Coman (male, Romania). nine-months fellows: Arnonas Finkelsteinas (male, Lithuania) and Sergey Alferov (male, Russia). Project 3) Characterisation of exocytosis from stem cell derived neurons. PhD student: Jan Toennesen (male, Denmark). nine-months fellow: Denisa Lojkova (female, Czech Republic). Project 4) Encapsulation of cells into polymers for stabilisation and self-assembling into arrays. PhD student Karolina Haberska (female, Poland). nine-months fellow: Marius Dagys (male, Lithuania). Project 5) Development of nano-Interdigitated Electrodes (nIDEs) and their arrays. PhD student: Lars Henrik Daeli Skjolding (male, Denmark). eight-months fellow: Genis Turon Teixidor (male, Spain). Additionally seven short term early stage researchers have been trained within this project, six for nine months, one for eight months. Most of these have / will have at least one scientific paper published in an international peer reviewed periodical. Of the 242 manmonths used in the project, 188 manmonths were used by trainees from within the European Union (EU) and 54 manmonths by trainees from outside the EU. Of the 242 manmonths 152 (63 %) were used to support male trainees and 90 (37 %) were used to support female trainees. The aim was to have 50:50 but this is possibly the main and only big failure of this project.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
BIONEL is a Marie Curie EST site at Lund University involving Analytical and Biochemistry/Biotechnology/Applied Microbiology/Cell-Organism/Neural Stem Cell Biology/Restorative Neurology/Solid State Physics. The aim is to provide early stage research traini ng in Bioanalytical Chemistry/Bionanotechnology/Bioelectrochemistry for stays from 9 months to a full PhD. The scientific content can be summarised as: Global parameters such as bioavailability/toxicity can only be assayed using living cells. The determina tion of these parameters motivates the objective of this project: to develop tools to monitor dynamic cellular processes with electrochemistry through (i) development of amperometric and impedance procedures for monitoring cell membrane integrity, redox si gnalling, and exocytosis. Focus will be at obtaining and understanding mediated and (possibly direct) electrochemical communication with both pro-and eukaryotic cells (ii) development of nano-Interdigitated Electrodes (IDE) for characterisation of exocytos is of catecholamine neurotransmitters from neurons, (iii) elaboration of methods for stem cell differentiation into different phenotypes by monitoring exocytosis using IDE arrays, (iv) encapsulation of cells into layer-by-layer built polymers for cell stab ilisation and self-assembling on IDEs, (v) development of cell and tissue based arrays. All fellows will work in projects involving at least two different disciplines under supervision of full and/or associate professors and with state-of-the-art equipment . Additional training in presentation skills, undergraduate supervision, safety, management will be provided. As a result of the training, all fellows will be able to publish scientific papers in peer reviewed international periodicals. The infrastructure will be open for the fellows with access to Internet, e-mail, remote databases etc. as well as advanced and graduate courses.
Оригинален текст от CORDIS (на английски).
Участници
- LUNDS UNIVERSITET · LUNDКоординаторШвеция
Връзки
Данни: CORDIS, © Европейски съюз