MMBNOTT · Research training in mathematical medicine and Biology at the University of Nottingham

Final Activity Report Summary - MMBNOTT (Research training in mathematical medicine and biology at the University of Nottingham)

This project involved the training of Marie Curie fellows on the early stage training (EST) network 'Mathematical medicine and biology at the University of Nottingham' (MMBNOTT). The network was hosted by the Centre for Mathematical Medicine and Biology in the School of Mathematical Sciences at the University of Nottingham. The Centre comprises applied mathematicians and statisticians who, in collaboration with biomedical researchers, use mathematical and statistical methods to investigate a wide range of topics across biology and medicine. The MMBNOTT network was designed to provide fellows with a broad training in relevant techniques and methods in mathematics and statistics, as well as in relevant areas of biomedical science, in order to give them the breadth of experience to undertake interdisciplinary research at new interfaces later in their careers. Fellows also received training in transferable research skills and pursued an individual research project that combined deterministic and statistical or stochastic modelling addressing a problem of biomedical relevance. Each fellow established a personal career development plan and was granted Marie Curie status by the University of Nottingham. Moreover, each fellow was assigned three supervisors, i.e. an applied mathematician, a statistician and an experimentalist, who provided guidance through a three year research project. European mobility was promoted by drawing all fellows from outside the United Kingdom. The 10 research projects and fellows supported by MMMBNOTT, with their supervisors, are listed below. 1. Fellow (Nationality): Bagdasar, Ovidiu (Romania) Research Topic: Cell adhesion: stochastic receptor-ligand binding under force (Project P3) Applied Mathematics Supervisor: Prof OE Jensen Statistics Supervisor: Prof FG Ball Experimental Supervisor (Institute/School): Prof PM Williams (Pharmacy) 2. Fellow (Nationality): Bokes, Pavol (Slovakia) Research Topic: Genetic regulatory networks (Project P4) Applied Mathematics Supervisor: Prof JR King Statistics Supervisor: Prof ATA Wood Experimental Supervisor (Institute/School): Dr M Loose (Genetics) 3. Fellow (Nationality): Chernyavsky, Igor (Russia) Research Topic: Placental structure: shape and flow analysis of the villous tree (Project P9) Applied Mathematics Supervisor: Prof OE Jensen Statistics Supervisor: Prof IL Dryden Experimental Supervisor (Institute/School): Dr L Leach (Biomedical Sci.) 4. Fellow (Nationality): Duduiala, Ciprian-Ionut (Romania) Research Topic: DNA dynamics: principal component analysis (Project P1) Applied Mathematics Supervisor: Dr JAD Wattis Statistics Supervisor: Prof IL Dryden Experimental Supervisor (Institute/School): Prof CA Laughton (Pharmacy) 5. Fellow (Nationality): Fischer, Thorsten (Germany) Research Topic: Membrane rafts: coagulation/fragmentation problems (Project P5) Applied Mathematics Supervisor: Dr GW Richardson Statistics Supervisor: Prof PD O'Neill Experimental Supervisor (Institute/School): Prof P O'Shea (Biomedical Sci.) 6. Fellow (Nationality): Januszewska, Anna (Poland) Research Topic: Single-molecule spectroscopy and cell signalling (Project P6) Applied Mathematics Supervisor: Prof JR King Statistics Supervisor: Prof FG Ball Experimental Supervisor (Institute/School): Prof SJ Hill (Cell signalling) 7. Fellow (Nationality): Laudanski, Jonathan (France) Research Topic: Neural processing of sound in the auditory system (Project P2) Applied Mathematics Supervisor: Prof S Coombes Statistics Supervisor: Prof ATA Wood Experimental Supervisor (Institute/School): Dr CJ Sumner (Neuroscience) 8. Fellow (Nationality): Panagiotopoulou, Vicky (Greece) Research Topic: Modelling drug resistance at the cell membrane level (Project P8) Applied Mathematics Supervisor: Prof OE Jensen Statistics Supervisor: Prof PD O'Neill Experimental Supervisor (Institute/School): Dr C Rauch (Vet School) 9. Fellow (Nationality): Pesando, Dayana Research Topic: Stem-cell differentiation pathways (Project P7) Applied Mathematics Supervisor: Prof HM Byrne Statistics Supervisor: Prof PD O'Neill Experimental Supervisor (Institute/School): Dr L Buttery (Pharmacy) 10. Fellow (Nationality): Taxidis, Ioannis (Greece) Research Topic: Neuroscience: spike trains in cultured neuronal populations (Project P10) Applied Mathematics Supervisor: Prof MR Owen Statistics Supervisor: Prof FG Ball Experimental Supervisor (Institute/School): Dr R Mason (Neuroscience). Full details of the project were available at the MMBNOTT website http://www.maths.nottingham.ac.uk/mmbnott/.

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