SNPCONGEN · Applying new genomic technologies into the field of conservation genetics
6РП — Действия „Мария Кюри“
- Период
- 2007-01-01 → 2008-12-31
- Финансиране от ЕС
- 156 316 €
- Участници
- 1
- Схема
- EIF
Линиите свързват координатора с партньорите.
Накратко на български
Генетичните маркери при застрашени видове, като вълци и орли, се анализират чрез нови технологии за по-точно определяне на тяхното разнообразие. Това помага за опазването на животните и разкрива заплахи като хибридизацията между два вида орли.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Final Activity Report Summary - SNPCONGEN (Applying new genomic technologies into the field of conservation genetics)
The objectives of the project were to characterise populations of endangered animal species by novel genetic markers, assess the efficiency of such markers, compared to the commonly used ones, and use obtained genetic information for scientific and conservation purposes. We studied a number of animal species of conservation concern, including mammals (wolves, coyotes, wolverines and lynxes) and birds (greater spotted eagle, lesser spotted eagle and white-tailed eagle). Our results imply that variability at commonly used microsatellite marker sets may not accurately reflect the underlying genomic diversity and novel genomic single nucleotide polymorphism markers would provide more reliable results. We also suggest that other markers, such as insertion-deletion polymorphisms (indels), could be an important source of genetic information; such markers are easy and inexpensive to genotype and have a high potential in studies of natural populations. Further, two topics of conservation and evolutionary importance were investigated in more detail. Genes associated with speciation of two closely related eagle species, greater and lesser spotted eagles, are more often found in sex chromosomes but the difference is not as large as found in other bird species thus far. The two spotted eagles are able to hybridise and, according to our large-scale genetic survey, the hybiridisation poses an important threat to the globally threatened greater spotted eagle.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Many animals are endangered due to human activity. Large predators belong to the most vulnerable species since they usually require large natural landscape, which is rare and fragmented nowadays. Hence, the populations of most large predators are small, isolated and probably genetically impoverished. Methods used so far to analyse genetic structure and diversity of populations have drawbacks and are not easily converted to automation on large-scales. Recently, genomic research of model organisms has highlighted single nucleotide polymorphisms (SNPs) as an abundant and easily genotyped source of genetic markers.The aim of current project is to integrate the use of SNPs into conservation genetic studies of endangered wild predators. Target species include mammals (wolf and wolverine), as well as birds (white-tailed eagle, greater and lesser spotted eagles). The project aims to identify SNPs from the genomes of these species, develop multiplex systems for their amplification and genotyping, compare SNP-diversities with those obtained using other methods, and integrate these markers into ongoing studies of inbreeding, monitoring and population genetics of endangered large predators.A better knowledge of the partition of the genetic diversity in the natural populations of these species may allow the reconstruction of population histories and redefining management strategies. The fellowship is intended to support the post-doctoral studies of Drulo Väli (Estonia) in Uppsala University (Sweden). Hence, the Project fulfils the objectives of EIF action work programme, which pursues the most promising researchers from EU and Associated Countries to undertake training through research in the European organisations most appropriate to their individual needs, and pretends to enhance research activity in the less-favoured regions of the EU and new Member States.
Оригинален текст от CORDIS (на английски).
Участници
- UPPSALA UNIVERSITY · UPPSALAКоординаторШвеция
Връзки
Данни: CORDIS, © Европейски съюз