DEFENCE SIGNAL · Mobility of signals in plant resistance to disease
6РП — Действия „Мария Кюри“
- Период
- 2007-01-01 → 2008-12-31
- Финансиране от ЕС
- 151 990 €
- Участници
- 1
- Схема
- EIF
Линиите свързват координатора с партньорите. За проекти отпреди 2014 г. CORDIS не винаги дава точни координати. Тези точки са на ниво град или държава.
Накратко на български
Сигналите, които растенията изпращат от заразена част към здравите тъкани, се проучват чрез модела Arabidopsis thaliana. Разбирането на тези процеси помага за по-добра защита на земеделските култури от бактерии, гъбички и вируси.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Final Activity Report Summary - DEFENCE SIGNAL (Mobility of Signals in Plant Resistance to Disease)
Plants have evolved complex mechanisms to protect themselves from diseases caused by different pathogens, including bacteria, fungi, and viruses. In one such mechanism, plants recognize an attacker and induce death of the infected part of the plant which prevents the pathogen from spreading. At the same time a signal is sent from the dying tissue to healthy parts of the plant that causes the induction of systemic acquired resistance (SAR). SAR protects plants from a broad range of different pathogens for a long time after the initial localized infection. Importantly, the SAR state is maintained at such low energy costs for the plant that it does not significantly affect its growth or seed yield. Pathogen infection of crop plants results in enormous economic losses in agriculture and we set out to map SAR signals in plants to understand processes underlying plant systemic immunity and potentially use this knowledge to protect crops from disease. For our studies we use the model plant species Arabidopsis thaliana (thale cress). This weed is one of the most studied plants worldwide due to its short lifecycle and ease of manipulation. Many technological advances have been made with Arabidopsis which allow relatively fast analysis of fundamental mechanisms that can then be used to further our understanding of other plant species, including crops. Earlier research had shown that small proteins, or peptides, may be involved in SAR signalling. Therefore, we compared the protein content of extracts of Arabidopsis plants that had been induced for the generation of SAR signals to that of similar extracts of mutant Arabidopsis plants that no longer generate or transmit such signals. So far, we found seven proteins potentially involved in SAR, the most promising of which are three enzymes that process larger proteins into peptides. A mutant no longer making one of these so-called proteases had a lowered capacity to mount SAR in response to bacterial infection. In future, we will investigate if plants making more of this enzyme are more resistant to infection. If so, the peptide produced by this enzyme could be a tool to help protect plants in the farm field from disease.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Plants have evolved sophisticated mechanisms of immunity against pathogens that limit the spread of disease and induce protection of systemic healthy tissues from secondary infections.The latter form of defence is called systemic acquired resistance (SAR) and is induced distally in plants by pathogens that trigger a local resistance response including programmed cell death. In essence, the plant sacrifices locally infected tissues to protect remaining cells from damage.Processes controlling local defence are increasingly well defined but the nature of long distance signals that induce SAR is a major outstanding question in plant biology today. SAR is a long-lasting potentiated state of resistance that acts against a broad range of pathogens. In this primed state, defences are not constitutively activated but are more rapidly and effectively triggered by subsequent pathogen attack.In agriculture, artificial induction of known defences can protect crops against disease but the energy costs are high to the pl ant and the crop yield penalty therefore severe. An important scientific breakthrough would be to identify plant signals, such as those controlling SAR, that potentiate defences against a broad range of pathogens without significant loss of yield.This project will apply state-of-the-art proteomics and lipid profiling technologies at high resolution to two model plants, Arabidopsis and Nicotiana benthamiana, in a comprehensive study to identify protein and lipid-derived SAR signals in crucifer and solanaceous plant species.A multi-disciplinary approach combining genetics, pathology, and molecular biology will be used to validate newly identified SAR signals and track movement of signals in the plant upon SAR induction.The project will provide a solid basis, including materials, for a future independent research programme and maturation of science-related skills towards the fellows independent research career in Europe.
Оригинален текст от CORDIS (на английски).
Участници
- MAX PLANCK SOCIETY FOR THE ADVANCEMENT OF SCIENCES, REPRESENTED BY MAX PLANCK INSTITUTE FOR PLANT BREEDING RESEARCH · MUNICHКоординаторНиво градГермания
Връзки
Данни: CORDIS, © Европейски съюз