BIOFET · Portable and disposable biosensor microarray based on FETs with a biofunctional gate to detect VOCs in breath
6РП — Действия „Мария Кюри“
- Период
- 2005-11-01 → 2007-09-30
- Финансиране от ЕС
- 168 798 €
- Участници
- 1
- Схема
- EIF
Линиите свързват координатора с партньорите.
Накратко на български
Сензори от въглеродни нанотръби се тестват за откриване на газове в дъха, като например азотен диоксид. Това помага за по-лесно и евтино диагностициране на заболявания като диабет.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Final Activity Report Summary - BIOFET (Portable and disposable biosensor microarray based on FETs with a biofunctional gate to detect VOCs in breath)
Carbon nanotubes (CNTs) gas sensitive films onto micromachined interdigitated gold electrodes are highly interesting devices. Scientifically speaking they allow to study the physicochemical properties of the considered gas sensitive materials and therefore obtain a more accurate and précis design of further devices, and technologically speaking these devices are easier, more reliable and cheaper to produce and implement than the capacitors so they are worthy to be studied because they are much more likely to be commercialised. Moreover CNTs based sensors show sensitivity to gases such as NO2 which is present in the breath of a person with diabetes -a disease that will affect more than 220 million people in the world by 2010- at room temperatures. For this reason the device can have a great commercial interest in the field of medicine and pharmacy. CNTs have been tested and CNTs non-covalently wrapped with active polymers and Pt/Pd/CuPc-decorated have also been studied. A gas set-up designed to study gas sensors has been used for testing the devices. Cross sensitivity is an issue for CNTs sensors and the response of the CNTs sensors does depend on the gas environment to which the CNTs have previously been exposed. The sensors have been also exposed to a series of test gases including NO2, NH3, CO and H2 and exhibited ppm detection at room temperature. Increasing the temperature not only reduced the recovery time of the sensors, but also increased the sensitivity to some gases.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
The growing interest in medicine in connecting different volatile organic compounds (VOCs) patterns in breath with diseases and disorders has increased the demand on breath tests devices. Nowadays, the required apparatus for breath analysis in the market a re bulky and difficult to operate and handle, they need a large amount of sample and several hours are needed to obtain a result. In addition, they are expensive (ranging from 600 to 25.000euro).Therefore, the project focus on developing a breath test dev ice which is fast, portable, extremely sensitive, with low cost and easy to miniaturize. The main challenge of the BIOFET project is the use of a tailor made biofunctional nanomaterial for gas-sensing purposes in a silicon micromachined array based on field effect transistors (FET). The biofunctional material consists in a coiled-coil peptide-based assembly of gold nanoparticles and it is possible to synthesize it using different types of peptides having the possibility of designing a more selective device.The transducer device, a silicon FET microarray, can provide a lot of key benefits for sensing target gases such as low fabrication costs and mass production (standard CMOS process), low power consumption, compact size, small weights, fast response (milliseconds) and the ability to readily integrate with signal conditioning electronics and other devices.The core of the multidisciplinary research project BIOFET converges on biological recognition mechanisms, nanosciences, materials research and techniques of analysis at a common research frontier. This innovative multidisciplinary technologically relevant research is crucial in forging strong links between industry and research as outlined in the Lisbon strategy and indeed throughout FP6.
Оригинален текст от CORDIS (на английски).
Участници
- IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE · LONDONКоординаторОбединеното кралство
Връзки
Данни: CORDIS, © Европейски съюз