MONOPHOSPHINESC3SYMM · Synthesis of chiral C3-symmetric tricyclic monophosphines and their application as chiral ligands in organometallic catalysis
7РП — „Хора“ (Действия „Мария Кюри“)
- Период
- 2008-10-01 → 2010-09-30
- Финансиране от ЕС
- 151 369 €
- Участници
- 1
- Схема
- MC-IEF
Линиите свързват координатора с партньорите.
Накратко на български
Синтезират се нови хирални фосфини, които служат като помощни молекули (лиганди) при химични реакции с паладий и рутений. Те помагат за създаването на специфични молекулярни структури, използвани в органичния синтез и катализата.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Цел на проекта
The primary scientific objectives of this project are twofold, 1) to develop a methodology to access novel enantiomerically pure chiral C3 symmetric tricyclic monophosphines and, 2) to verify their utility as chiral ligands in transition metal catalysed asymmetric reactions. This project will involve both organic and organometallic chemistry. Organic chemistry will be used for the preparation of these novel C3 symmetric tricyclic monophosphines using known methodologies such as the ring-closing-metathesis reaction, 1,4 addition reactions and the Heck reaction. Organometallic chemistry will be used for the synthesis, isolation, purification and characterisation of novel chiral transition metal catalysts based on these phosphines. The chemical and physico-chemical characteristics of these catalysts will be studied and these catalysts will be tested in asymmetric transformations. In particular, attention will be turned toward palladium-catalysed asymmetric allylic alkylation reactions, palladium-catalysed asymmetric hydrosilylation of alkenes with trichlorosilane and ruthenium-catalysed asymmetric ring-closing-metathesis reactions.
Оригинален текст от CORDIS (на английски).
Участници
- FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA · TARRAGONAКоординаторИспания
Връзки
Данни: CORDIS, © Европейски съюз