FP7Обмен на изследователи2011–2014

BIOMIMEM · Biomimetic Membrane Systems

7РП — „Хора“ (Действия „Мария Кюри“)

Период: 2011-03-01 → 2014-02-28
Финансиране от ЕС: 214 200 €
Участници: 2
Схема: MC-IRSES

Линиите свързват координатора с партньорите.

Накратко на български

Биомиметичните мембранни системи имитират структурата на клетъчните мембрани, за да се проучи как те взаимодействат с протеини и пептиди. Това помага за разбирането на биохимичните процеси в живите организми и създаването на устройства за биосензинг и тестване на лекарства.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Biomimetic Membrane Systems

Currently biomimetic membrane systems include model lipid monolayers at the soft air/liquid interface, solid-supported lipid bilayers, patterned solid-supported lipid bilayers and polymer-cushioned liposomes. Four partner groups from MPIKG (Germany), ICBMS (France), ICCAS (China) and HIT (China) have focused on these systems and made outstanding progress. Thanks to the support of the BIOMIMEM project, they exchanged their research experiences and knowledge in the field of biomimetic model membrane systems, and carried out joint experiments by means of person exchanges including Ph.D. students, forming an international community working on the biomimetic model membrane systems. By collaborating, the phase behaviour of different model lipid membranes and the mechanism of their interaction with peptides/proteins have further been illustrated, what is helpful to understand biochemical processes related with cell membrane in living organisms, and to design novel nano-bio-devices for drug screening, bio-sensing and bio-detection.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Biological membranes play a central role in the living organization, but it is difficult to study protein-protein and protein-membrane interaction under controlled conditions inside of the living cells. Pioneering works have been carried out, indicating that biomimetic membrane systems such as lipid monolayers, liposomes, solid-supported or polymer-cushioned lipid membranes, can not only serve as biophysical models to study protein-protein and protein-membrane interactions, but also can be used to the design of biosensors and drug carriers. We feel it is extremely timely to form a partnership that combines researchers who have significantly contributed to this topic with the hope that our combined effort will lead a further and deeper understanding of the structure and functions of biological membranes.The IRSES project BIOMIMEM aims at connecting groups in the Germany (MPIKG), France (Lyon) and China (ICCAS and Harbin) which are working on biomimetic membrane systems. The exchange programme is organized into definite but complimentary 4 work-packages (WPs) that are executed by the combined effort of the above-mentioned 4 partners. This project brings together leading researchers with broad, complementary expertise: from biophysical chemistry, biochemistry, theoretical chemistry, to the more applicable aspects of nanobiotechnology, to form a team with the common goal of understanding the fundamental nature of biological membranes and developing new biosensors and drug carriers. Moreover, it will support and reinforce collaboration among the participants, help to educate young researchers, and help to develop and establish future long-term research collaboration between EU and China.

Оригинален текст от CORDIS (на английски).

Участници

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV · MUNCHENКоординаторГермания
UNIVERSITE LYON 1 CLAUDE BERNARD · Villeurbanne CedexФранция