FP7Индивидуална стипендия2011

JUSTA · Jumbled Strings: Theory and Applications

7РП — „Хора“ (Действия „Мария Кюри“)

Период
2011-08-03 → 2011-11-02
Финансиране от ЕС
244 075 €
Участници
1
Схема
MC-IEF

Линиите свързват координатора с партньорите.

Накратко на български

Париховите вектори и низове анализират броя на символите в дадена последователност, вместо техния ред. Това помага за по-бързото търсене, сравняване и възстановяване на данни в биоинформатиката.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Jumbled Strings: Theory and Applications

This project aimed at making decisive steps towards a theory of Parikh vectors and strings, with particular attention to applications in bioinformatics. In particular, the objectives included the development of dedicated data structures and algorithms for Parikh vectors, in the three problem areas of search, comparison and reconstruction. The project was interrupted after only three months, because the fellow, Dr Zsuzsanna Liptak, was offered a permanent position as Assistant Professor at the University of Verona. In this short period of three months, she was still able to make progress towards several of the goals stated in the project proposal (work plan). The current results need further work but are expected to eventually result in publications at international conferences and/or international journals. The fellow was also able to benefit from some training opportunities offered at the host institution, as well as at an international conference she attended. She is dedicated to pursuing the project further. The website of the project is http://www.dia.unisa.it/~zsuzsa/justa, and the fellow can be contacted at zsuzsanna.liptak@univr.it.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

We propose to investigate a number of algorithmic problems on jumbled strings, where we refer to a string t as a jumbled version of string s if t's positions can be permuted such that it is transformed into s. In other words, the two strings have the same Parikh vector, where the Parikh vector counts the number of occurrences of each character. For example, the strings AAGACGT and AAACGGT both have Parikh vector (3,1,2,1). All strings with the same Parikh vector build an equivalence class, which we refer to as a 'jumbled string.' We want to develop algorithms and dedicated data structures for searching, storing, comparing, and identifying jumbled strings.Jumbled strings have important applications in bioinformatics, above all in interpretation of mass spectrometry data; but they have also been applied to alignment, pattern discovery in biological strings, or SNP detection. Searching for a jumbled pattern in a text constitutes a special case of approximate string matching, and is thus of particular interest in the pattern matching field. Similar problems regarding unique reconstruction of strings have been investigated in the area of formal languages.The project involves both theoretical and practical parts. Besides searching for asymptotically optimal procedures for different models of the source which generates the text, we will also test on real instances of biological and textual data. We are not only interested in theoretically optimal algorithms but focus on algorithms that work well in practice. Thus, we consider also heuristics and ad hoc methods to enhance the practical implementation of our methods.The project will enable the fellow to greatly enhance her competencies in algorithms development and formal languages, while training in information theory and extremal combinatorics, benefitting from the expertise at the host institution. This will constitute a major step in her career towards a professorship in algorithmic bioinformatics.""

Оригинален текст от CORDIS (на английски).

Участници

  • UNIVERSITA DEGLI STUDI DI SALERNO · Fisciano SaКоординаторИталия

Връзки

Данни: CORDIS, © Европейски съюз