генно инженерство

GT-GM1 · Ex vivo gene therapy for GM1-gangliosidosis

iMIND · iPS-derived MIcroglia and Neuroinflammation in Dementia

2 партньори · 2 държави

CRISPR-KissCas9 · Challenging the KNDy Hypothesis Using CRISPR-Cas9 Genome Editing: Evaluation of the Role of Neurokinin B and Dynorphin in Kiss1 neurons in the Control of Fertility

EPIOBESITY · Unravelling the hypothalamic epigenetic code behind obesity.

BacDrug · Bacterial membrane vesicles a novel delivery system for the treatment of multi-drug resistant Gram-negative bacterial infections.

SYNKIT · Synthetic Natural Killer Cells for Immunotherapy

OCTOBER · Control of cell identity in pluripotent and germline cells by OCT4 orchestration of chromatin binding and enhancer regulation

TRYPTISSUE · Characterising Trypanosoma tissue tropism: new perspectives for variant surface glycoproteins

ARCH · AGE-RELATED CHANGES IN HEMATOPOIESIS

19 партньори · 10 държави

Genetic Vaccine · Study the therapeutic and preventive potential of targeting oncogenic mutations with CRISPR-Cas9 technology

SaPhaDe · Know your enemy: systematic discovery of Salmonella anti-Phage Defences for the improved design of phage therapeutics

2 партньори · 2 държави

LEVERAGE mRNA · Laboratory Evolution of Virus-likE pRotein cAGes for Eukaryotic mRNA delivery

DADA2GT · Development of gene therapy and genome editing strategies to treat adenosine deaminase 2 deficiency

InvADeRS · Investigating the Activity of transposon Derived Regulatory Sequences in the placenta

TFZN · Understanding the mechanisms that govern organ morphostasis and repair

MetaTarGet · Targeting metabolic regulation in metastasis formation

Exh-Res-CART · Exhaustion-resistant CAR-T cells for the treatment of solid tumours

SOS-CROPS · Solving the tangled ontogenesis of the stem for sustainable crops

BICE · Circuit mechanisms for behavioral choice from complete CNS activity and connectivity maps

ARCS · Elucidating the gene exchange networks of antibiotic resistance genes in clinical sewage microbiomes

MsgRNA · Modification of single guide (sg) RNA in CRISPR-Cas9 gene editing Tool

VESYNECH · Determination of bacterial vesicles interactions in the most abundant marine cyanobacteria and its potential applications

FrATGaria · Identification of the role of autophagy during fruit ripening and stress resistance in Strawberry: Autophagy manipulation as a way to improve Strawberry fitness

R-FunSel · In vivo functional screening via CRISPR-Cas9 to systematically identify cardiomyocyte receptors as targets for the innovative therapies for myocardial infarction and heart failure