biomolecules

Illuminate-AMR · Single-molecule visualization of individual multi-drug efflux pump activity in living bacteria with nanophotonic biochips

PROTACs · Design, synthesis and biological evaluation of PROteolysis-TArgeting Chimeric (PROTAC) molecules as anticancer agents

mcMINFLUX · Tracking conformational dynamics of cohesin with MINFLUX

IMPROVING-GT · Innovative strategies to increase engraftment of engineered hematopoietic stem cells and bypass genotoxic conditioning, toward the next-generation gene therapy

CAREQiPSC · Cartilage derived from equine induced pluripotent stem cells: an in vitro and ex vivo One Medicine approach for osteoarthritis

PrediKSion · An evolutionary guided and experimentally validated computational pipeline to unravel new polyketide synthase functionality

EGR · The role of genetic redundancy in adaptive evolution of efflux pumps

HSV1_Single_Molecule · Single molecule imaging of herpes simplex virus type 1 DNA replication

CRISIS · Chytridiomycosis resistance through sexual selection

FEPS · Evolution on an island continent: feeding ecology of Pleistocene sloths

SYNarch · Understanding the nanoscale synaptome architecture of the brain

COVISENSE · Simultaneous detection of carbon monoxide and viscosity changes in cells using bimetallic fluorogenic probes

Chemical Mutagenesis · a powerful tool for the creation of a library of nanobodies

AxoMatrx · How do dynamic changes extracellular matrix guide regenerative events in Axolotl?

2 партньори

SynBioLipid · Synthetic biology for microbial lipids production from lignocellulosic biomass using multi-functional synthetic consortia

SYN-CHARGE · Novel avenues of action for a hallmark disordered protein of Parkinson's disease

NECESSITY · New prECision thErapieS for uveal melanoma (targeting the Gαq/GNAQ oncogenic Signaling cIrcuiTrY)

2 партньори · 2 държави

EVPERS · Extracellular vesicles as a tool to predict drug clearance and improve precision pharmacotherapy

EXOonRNA · Delineating the kinetic RNA interactome of nuclear exosome adaptor complexes

HeliTrans · Helical foldamers with tunable channels for transmembrane water and ion transport

DNA-Rep-EM · Origin-dependent DNA replication visualised by Cryo-EM

NanoFusion · Effect of nanoparticles on membrane fusion

GLYCOMIMIC · Gaining insights into Enzymes Transition States: Superacid as new tool to design specific CAZymes inhibitors.

ENDOLOGISTIC · Endocytic logistics of defense signaling in plants