mutation

VirION · Inter-organelle crosstalk in viral infections: identifying peroxisome-related targets for novel broad-spectrum antiviral strategies

21 партньори · 10 държави

IMMUNOPA-8T · Deciphering OPA1 regulation and function in human CD8⁺ T cells across scales

CORALOMICS · Tracing somatic evolution in corals with multi-omics: implications for longevity and adaptation

3 партньори · 3 държави

TranscriptAccuracyAD · Leveraging long-read RNA-sequencing to understand the pathophysiology of familial and complex Alzheimer’s disease

nanoGET · Nanopore based evaluation of genomic, epigenetic and transcriptomic impact of gene editing

KRATOS · KRAS Targeting in Oncogenic Systems: reconstructing the KRAS signalling network to identify optimal drug combinations

3 партньори · 2 държави

LGT-GRIP · Lateral Gene Transfer: Genomic Recruitment, Integration, and Persistence

TESexReg · Elucidate TE Impact On Sex Chromosome Regulatory Evolution

PEAKRAS · A Dual Amplification Photoelectrochemical Platform for KRAS Mutation Detection

Na-CPVT · Molecular, cellular, and pharmacological characterization of a new modality of familial arrhythmia

NORMA · uNreveal the rOle of SpaRtin in MitochondriA

3 партньори · 2 държави

HDFACT82 · Functional characterisation of CCDC82 and its interaction with FACT in Huntington’s disease

ThermAPP · When neurons run hot: γ-Secretase thermal vulnerability as an Alzheimer's pathogenic mechanism

GPMVreconstituteEGFR · EGFR protein condensation as a regulator of Ras activity

2 партньори · 2 държави

GASTRO-PD · Investigating non-motor symptoms of Parkinson’s Disease using Drosophila melanogaster as model

DiagMDS · Towards novel approaches for Myelodysplastic Syndromes diagnosis to Strengthen Research Human Capital with Cross-Sectoral and Interdisciplinary Staff mobility

17 партньори · 9 държави

DYNAGEN · Mechanisms of mChr-mediated genome dynamics in the cereal blast fungus Magnaporthe oryzae

Mech-ATM · Exploring ATM/ATR Signaling at the Crossroads of DNA Repair and Mechano-transduction

EvoTolRes · Divergent evolution of drug resistance and tolerance in a fungal pathogen

MPN2AML · Identification of novel genetic regulators governing leukaemic transformation from myeloid proliferative neoplasms

2 партньори · 2 държави

SNAREopathies · High-throughput screen for disfunctions in GABA-switch in human neuronal models of SNAREopathies

AI-EvoYeast · Harnessing Genomic Instability with Al-Driven Adaptive Laboratory Evolution for Accelerated Yeast Bioproduction

WILSON · Wilson transporter ATP7B: Interactions, Lipids, Structure and RegulatiON

EpiGen-LC · Epigenetic and Genetic interplay in Liver Cancer