epigenetics

mC-EVOLVE · The evolutionary biology of crop plant DNA methylation

2 партньори · 2 държави

MonitorMS · Monitor Multiple Sclerosis evolution using body fluids derive cell-free epigenomics

EpiSoDi · Epigenetic Pathways of Socioeconomic Disparities across the lifespan

REASONING · The moleculaR mEchAnismS Of dNa methylatIon reprogrammiNg in Arabidopsis sexual lineaGe

DrosoParamutation · Unraveling the role of transgenerational epigenetic inheritance mediated by paramutation in natural animal populations.

XICUT · Epigenome establishment and maintenance of the inactive X chromosome in response to DNA double-strand breaks in mammalian cells

2 партньори

ChroMet · Elucidating the role of macroH2A1.2 histone variant as a metabolic sensor in the epigenetic regulation of leukaemia cell fate.

SCRIBE · Stem cell riboregulation: a new layer to control self-renewal, differentiation and metabolism

EpiAAVTherapy · Characterizing the chromatin landscape of Spinal Muscular Atrophy in response to AAV9 mediated gene therapy

2 партньори

M-Y-cro · Metabolism-YEATS-crosstalk: Elucidating metabolic dependencies of epigenetic YEATS action

Remin-T · Dissecting the molecular basis of immunological memory in human T cells

EpiDevoTimeMachine · Connecting the dots going backwards: An epigenetic memory recorder to trace ancestry during mouse gastrulation.

PEARL · Novel biomarkers of pollution in avian models: Paternally-transmitted Epigenetic Alterations in Response to heavy metaL exposure

PEZ · Primordial Germ Cells Environmentally-driven fate in Zebrafish

EPIC · Mechanism and significance of de novo gene methylation during reproduction in Marchantia

2 партньори · 2 държави

MOM2CHILD · Impact of maternal nutritional status and microbiota on child anthropometric and metabolic development

3 партньори · 2 държави

BrainCircHD · CircHtt in brain development and Huntington`s Disease: elucidating in vivo brain functions of a novel circular RNA molecule stemming from the Htt locus

EpiSeedLink · From seed to seedling: Epigenetic mechanisms of priming to design strategies for crop improvement

24 партньори · 7 държави

HDACbyCRYOEM · High-resolution cryo-EM structures of the human and yeast Sin3 histone deacetylase complexes

MM_BH3_CutTag · Parallel epigenomic and apoptotic profiling to identify targetable sensitivities in Multiple Myeloma

2 партньори · 2 държави

ForgettingNAFLD · Unravelling the pathogenic cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver disease

EstroGen · Reciprocal interactions between hypogonadism and epigenetic modifications: A path for the development of personalized treatments for depression

GENESPERSIVE · DISPERSIVE GENOMES: Epigenetic potential as mediator of phenotypic plasticity and natal dispersal

CHROMISE · Identifying Variable Chromatin Modules using single-cell epigenomics