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Science by subject

Pick a subject and see real European projects behind it.

Biology and life

How do scientists study living things, from single cells to whole ecosystems?

Ages 11-19

Chemistry

What new materials and substances do chemists create, and what are they for?

Ages 13-19

Physics and space

From quantum particles to distant galaxies: what do we still not know?

Ages 12-19

Computing and AI

How do computers learn to recognise, predict and help?

Ages 11-19

Mathematics

Where do abstract mathematical ideas turn up in the real world?

Ages 13-19

Geography, climate and the Earth

What is happening to the climate, the oceans and the soil, and how do we measure it?

Ages 10-19

Medicine and health

How are new medicines made, and how do scientists fight disease?

Ages 12-19

Technology and engineering

How are the machines, materials and energy of the future designed?

Ages 11-19

History and archaeology

How do archaeologists and historians read the traces of the past?

Ages 10-19

Languages, art and culture

What do languages and the arts reveal about the people who make them?

Ages 10-19

Society and economics

How do researchers work out how societies and economies function?

Ages 13-19

🧬 Biology and life

Showing 96 of 1,390 projects

HE2025–20272 countries

DISCOVER · Dynamic response of cells to viscoelastic forces

Mechanobiology explores how physical forces affect cellular processes, providing insights into areas like embryogenesis and tumor growth. Cells exert forces onto their environment; the tissue in which they live. These tissues are not purely elastic.

Data: CORDIS, © European Union

HE2025–20272 countries

OUTCOME · ecO-evolUTionary dynamics in COMmunitiEs

Ecological communities are composed of a vast number of interacting species. Individuals of different species interact for feeding, survival or many other services, like protection or transport. Such interactions form ecological networks.

Data: CORDIS, © European Union

HE2024–20262 countries

MalDiProT · Malaria diagnosis and prognosis with an electrokinetic-driven aptamer-based lateral flow assay.

Malaria remains one of the world’s most persistent infectious diseases, causing hundreds of thousands of deaths every year and placing nearly half of the global population at risk. Although the disease is most common in sub-Saharan Africa, Europe also faces increasing numbers of imported malaria cases due to internatio…

Data: CORDIS, © European Union

HE2024–20262 countries

LuxSoM · LuxR solos as major proteobacterial players of cell-cell signaling in the plant microbiome

About 60 to 70% of soils in the EU are subject to severe degradation processes: erosion, pollution, loss of biodiversity, salinisation and sealing; this is the result of unsustainable land use and overexploitation of agrochemicals. Microbial-based solutions, in agriculture, are now becoming important alternatives as an…

Data: CORDIS, © European Union

HE2024–20262 countries

SUPERSET · Semiconductor free biophotoelectrodes for solar fuel production

The soaring demand for energy and use of fossil fuels has resulted in the release of vast amount of greenhouse gases and climate change. Developing photoelectrochemical devices for solar fuel production is one of the strategies to address these issues. The use of photosynthetic proteins as photoactive components could…

Data: CORDIS, © European Union

HE2024–20262 countries

HeartRepairKIT · Structural, kinetic, and biophysical analysis and engineering of KIT.METRNL signalling to boost heart tissue regeneration after myocardial infarction

Cardiovascular diseases are the leading cause of death worldwide, with millions of patients suffering from long-term complications after heart attacks. One of the major medical challenges is the limited ability of the heart to regenerate damaged tissue, which often results in reduced quality of life and high healthcare…

Data: CORDIS, © European Union

HE2024–20275 countries

CanDoIt · Intelligent Breast Cancer DiagnOsis and MonItoring Therapeutic Response Training Network

A breakthrough in precision diagnostics and treatement for breast cancer Breast cancer diagnosis and treatment face persistent challenges, with current methods often lacking the precision and ease of use required for optimal patient care. Existing techniques may lead to misdiagnosis, delayed intervention or non-adapted…

Data: CORDIS, © European Union

HE2024–202711 countries

BeyondTheEdge · Higher-Order Networks and Dynamics

The scientific aim of the MSCA-DN BeyondTheEdge is to identify the role of nonpairwise ‘higher-order’ interactions in the emergence of complex dynamical behaviour of networks of interacting units. Traditionally, networks are equated with graphs that consist of units together with edges as pairwise relations between two…

Data: CORDIS, © European Union

HE2024–20276 countries

ZooCELL · Tracing the evolution of sensory cell types in animal diversity: multidisciplinary training in 3D cellular reconstruction, multimodal data analysis and science outreach.

Sensory cells in marine invertebrates play a fundamental role in detecting environmental cues and translating them into biological responses that enable survival, feeding, reproduction, and interaction with the environment. These cells detect chemical and mechanical stimuli, gravity, temperature, and salinity, guiding…

Data: CORDIS, © European Union

HE2024–20279 countries

PHABB · Pathogens of Algae for Biocontrol and Biosecurity

Micro- and macroalgae are fundamental components of aquatic ecosystems and will play an increasingly important role in our future. While many algae are beneficial, such as seaweeds used for food, biofuels, pharmaceuticals, and cosmetics, others can have detrimental effects. Harmful algal blooms (HABs), for instance, de…

Data: CORDIS, © European Union

HE2024–20279 countries

NMR-IMPROV · NMR relaxation tools for improving and protecting quality of dairy products

NMR-IMPROV introduces an innovative approach to examining the properties of dairy products through advanced Nuclear Magnetic Resonance (NMR) relaxation techniques, including Fast Field Cycling and Time-Domain NMR. This concept is based on the understanding that the macroscopic properties of dairy products are determine…

Data: CORDIS, © European Union

HE2024–20252 countries

Den-LLZO · Understanding the origins of dendrite formation and growth in LLZO solid electrolytes

Rechargeable batteries are a key enabling technology for the transition toward sustainable energy systems and the widespread adoption of electric mobility. In particular, solid-state batteries based on lithium metal anodes and ceramic electrolytes such as LLZO offer significant advantages over conventional lithium-ion…

Data: CORDIS, © European Union

HE2024–20278 countries

ENRICH · Molecular receptors enrich methylated and acetylated peptides for ultra-sensitive proteomics to explore the hidden modified proteome in disease

ENRICH is a Horizon Europe – MSCA Staff Exchanges project built around a practical need in protein analysis: post-translational modifications (PTMs) on histone proteins are biologically important, but they are often difficult to detect and study because of their low concentration and complex matrices. Enrichment steps…

Data: CORDIS, © European Union

HE2024–20262 countries

SUMOMyePath · UNVEILING THE ROLE OF SUMOYLATION AS NOVEL MOLECULAR PATHWAY IN MYELIN BIOLOGY; IMPLICATION IN NEURODEVELOPMENT AND DEMYELINATING PATHOPHYSIOLOGY.

Myelin is an essential biological structure that allows the nervous system to transmit information rapidly and efficiently. It is produced by specialised glial cells called oligodendrocytes in the central nervous system. When myelin is damaged, lost, or not properly maintained, neurological function can be severely aff…

Data: CORDIS, © European Union

HE2024–20262 countries

PALOMA · A Palaeoenvironmental Investigation of Amazonian Lowland Sensitivity to Climatic Drivers Using Pollen-based Modelling Approaches

This MSCA project was entitled “A Palaeoenvironmental Investigation of Amazonian Lowland Sensitivity to Climatic Drivers Using Pollen-Based Modelling Approaches”, hereafter Project PALOMA (European Fellowship, Grant ID 101105420), and it was hosted at Geosciences Barcelona (GEO3BCN-CSIC). Its overarching aim was to ini…

Data: CORDIS, © European Union

HE2024–20278 countries

IMMERGE · Storming Immune Monogenic Conditions through Multiomic and Gene Editing Approaches

The human immune system is our natural defense against infections and abnormal cells like cancer. It relies on a carefully balanced network of genes that produce receptors, signaling molecules, and transcription factors—all influenced by environmental and epigenetic factors. When a single gene is mutated, as seen in In…

Data: CORDIS, © European Union

HE2024–20288 countries

BullNet · A cutting edge integrated approach to sperm biology and associated reproductive biotechnologies to assist the dairy and beef industries meet growing societal, environmental and economic demands

The overall research aim of BullNet is to use cutting-edge molecular and machine-learning techniques, coupled with functional and applied methods to unravel the underlying sperm biology surrounding compromised fertility of individual bulls, which is a complex biological question. Developing an in-depth understanding of…

Data: CORDIS, © European Union

HE2024–20288 countries

SIGSYNCELL · Engineering biological signaling pathways using synthetic cells

The 21st century’s challenges in climate, energy, and health demand new biotechnologies. Synthetic biology offer solutions with consistency and reproducibility unattainable by living cells, but models for integrated synthetic cells systems are lacking. While the IT industry’s complex microsystems – based on transistors…

Data: CORDIS, © European Union

HE2024–20278 countries

SEASOUNDS · Innovative marine soundscape characterization to effectively mitigate ocean and sea noise pollution

SEASOUNDS aims to better characterize and predict marine soundscapes in various European eco-regions (e.g., parts of the Mediterranean and the Baltic Seas, the Venice Lagoon, the Norwegian fjords) where the scarcity of scientific data, upon which decisions are based, as well as the difficulties associated with sound fi…

Data: CORDIS, © European Union

HE2024–20287 countries

GLYCO-N · GLYCOprotein N-glycosylation from non-life to eukaryotes: a Doctoral Network to expand the knowledge on a ubiquitous posttranslational modification of proteins

The GLYCO-N training network aims at training Doctoral Candidates (DCs) to acquire the skills to develop different innovative strategies to 1) understand the diversity and structural complexity of archaeal, microalgal and viral N-glycosylation and 2) harness this knowledge for new solutions in biomedicine and biotechno…

Data: CORDIS, © European Union

HE2024–20287 countries

ENSCC · European Network on the Supramolecular Chemistry of Carbohydrates

Context and Objectives Carbohydrates mediate critical biological processes, yet natural Carbohydrate-Binding Molecules (CBMs) used to target them are costly, delicate, and often lack selectivity. The ENSCC project addresses this problem by uniting European experts to design robust, cost-effective artificial CBMs. Along…

Data: CORDIS, © European Union

HE2024–20262 countries

INTERACT · Skin microbial metabolites and antimicrobial peptides at the interface of skin-gut inflammation

Skin diseases are among the most common health conditions affecting over 900 million people according to the World Health Organization. Skin diseases often co-occur with gut disorders and bidirectional crosstalk along the skin-gut axis influences both gastrointestinal and skin health. Inflammatory skin diseases (ISDs)…

Data: CORDIS, © European Union

HE2024–20252 countries

NIR-NanoCAR · Near-Infrared Photothermal Nano-CAR Immunotherapy mediated by engineered exosomes targeted to pancreatic cancer with mutated KRAS

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers and continues to show limited response to current therapeutic approaches, including immunotherapy. Novel therapeutic approaches capable of overcoming tumour immune resistance and improving selective drug delivery are therefore urgently needed.…

Data: CORDIS, © European Union

HE2024–20288 countries

AGRI-DRY · Dryland agriculture and Land use; past, present and future resilience [AGRI-DRY]

AGRI-DRY is a multidisciplinary research and training network addressing the need for sustainable food production and ecological resilience in dryland regions, which support around 40% of the world’s population. Focusing on the Mediterranean Basin, North Africa, and Southern Africa, the project examines long-term inter…

Data: CORDIS, © European Union

HE2024–20262 countries

MULTI-SOFT · Multi-scale and Multi-physics Modelling of Soft Tissues

Soft biological tissues—such as skin, vessels, and tumors—exhibit highly complex mechanical behavior driven by nonlinear, time-dependent, and multiphysical interactions. Traditional models often treat these effects in isolation, failing to explain critical phenomena like growth-induced instability, delayed buckling, or…

Data: CORDIS, © European Union

HE2024–20252 countries

INFLAMAM · Role of Mitochondria-Associated ER membranes on microglia activation: implications for Alzheimer's disease.

Alzheimer’s disease (AD) is a common debilitating age-related neurodegenerative condition characterized by progressive cognitive decline and pre-symptomatic accumulation of amyloid-β. Over 14 million people in Europe are living with dementia (60-70% AD diagnosis), which is projected to double by 2050. Currently, there…

Data: CORDIS, © European Union

HE2024–20253 countries

ECHOS · Exploring aCtive edible materials based on pHenolic-biocOnjugates from agro-industrial by-products for Sustainable and healthy future food packaging

The ECHOS project addresses the growing need for sustainable and circular food packaging solutions in line with the EU Circular Economy Action Plan and Bioeconomy Strategy. Conventional plastic packaging remains a major source of environmental pollution, while large volumes of agro-industrial by-products are generated…

Data: CORDIS, © European Union

HE2024–20262 countries

BioCiTrees · An integrative understanding of the role that urban trees plays for people and nature

Cities face increasing pressure to optimise living conditions while ensuring a high quality of life. Urban trees provide multiple benefits, including air quality regulation, recreational opportunities, and habitat for biodiversity. Designing green urban areas that maximise these benefits requires understanding the mech…

Data: CORDIS, © European Union

HE2024–20262 countries

SONIC · Sense Of Number in Invertebrate Cognition

Understanding how numerical cognition emerges across species is a central question in cognitive science and evolutionary biology. True counting abilities — such as recognising numbers across different procedures and sensory modalities or spontaneously ordering them along a mental continuum — are often considered unique…

Data: CORDIS, © European Union

HE2024–202710 countries

CLEAR · “CLEAR”: Cell Envelope Antibacterials

Antimicrobial resistance (AMR) has escalated into a global health crisis, with more than one million estimated deaths in 2019 attributable to infections with antibiotic resistant pathogens. Gram-positive bacteria are responsible for a large share of these and among them, the methicillin resistant Staphylococcus aureus…

Data: CORDIS, © European Union

HE2024–202710 countries

ProgRet · European Training Program to Understand, Diagnose and Treat Autosomal Dominant Retinal Diseases

ProgRET is a multidisciplinary and intersectoral European training network focusing on the mechanisms, diagnosis and therapy of dominantly inherited retinal diseases (IRD). IRD represent a major cause of blindness, affecting 350,000 people in Europe. IRD have long been considered incurable, however major advances have…

Data: CORDIS, © European Union

HE2024–20252 countries

ClimDivE · Influence of Climate variability on the Gravettian cultural Diversity and Evolution

Throughout history, humanity has displayed remarkable resilience by diverse cultural adjustments to changing conditions. In the face of unprecedented environmental shifts brought about by global warming, societies are grappling with the urgent need to adapt. In this context, the ClimDivE project proposes to draw on the…

Data: CORDIS, © European Union

HE2024–20289 countries

MIRACLE · Multilevel inflammatory regulation in cardiometabolic disease

The MIRACLE programme brings together leading academic and biotech industrial partners to train the next generation of innovation-minded researchers who can advance precision medicine approaches for cardiometabolic diseases (CMD). CMD are among the most common and burdensome health conditions worldwide. This group of c…

Data: CORDIS, © European Union

HE2024–20273 countries

RISEN · Hip at what cost? How the human pelvis adapted to bipedalism and childbirth

When our ancestors began walking upright millions of years ago, the human pelvis underwent a dramatic transformation. This shift to bipedalism — walking on two legs — was one of the defining moments in human evolution, but it came at a cost. As the pelvis reshaped itself to support an upright posture, and as the human…

Data: CORDIS, © European Union

HE2024–20262 countries

SUMAC · TrendS and Uncertainties in Mercury (Hg) Atmospheric Chemistry

Mercury (Hg) is a toxic heavy metal that bioaccumulates in aquatic food chains, endangering human health through the consumption of seafood. The atmospheric chemistry of Hg determines how far it can be transported and where it will ultimately deposit, since elemental mercury (Hg(0)) is insoluble and long-lived in the a…

Data: CORDIS, © European Union

HE2024–20262 countries

RhECAST · Rural landscape hEritage and CArbon sequeSTration

RhECAST (Rural Landscape Heritage and Carbon Sequestration) addresses the growing need to reconcile climate change mitigation with the preservation of Europe’s cultural landscapes. Across many European regions, traditional agroforestry systems and historical agricultural landscapes have been progressively abandoned or…

Data: CORDIS, © European Union

HE2024–20262 countries

DesiRTA · Localize and Controlled co-delivery of AuNPs conjugated siRNA by Cationic Shear-thinning Gel Matrix for Treatment of Arthritis (DesiRTA)

DesiRTA: A Targeted Nanotherapeutic Approach for Revolutionizing Arthritis Treatment Arthritis, a prevalent global health concern affecting over 350 million individuals, substantially burdens healthcare systems. This chronic condition, characterized by joint pain, edema, and restricted mobility, significantly impairs p…

Data: CORDIS, © European Union

HE2024–20262 countries

ElectroAD · Novel hybrid electro-anaerobic digestion system for simultaneous antibiotics removal and bioenergy recovery

Antibiotics are now recognised as pollutants of global concern. Their widespread use has led to residues in the environment that contribute to antimicrobial resistance (AMR), a major threat to public health and ecosystems. Wastewater treatment plants are hotspots for antibiotic residues and resistance genes, yet conven…

Data: CORDIS, © European Union

HE2024–20276 countries

PROHITS · Prokaryote proteomics at high temperature for single cells

A sustainable climate and an ecosystem-friendly economy demands novel "cell factories", in which organisms convert renewable biomass into various biomaterials that would otherwise be derived from fossil fuels or (harsh) chemistry. Especially promising is the use of thermophilic bacteria and archaea that operate at high…

Data: CORDIS, © European Union

HE2024–20262 countries

ADEEPSLEEP · Focusing on deep sleep-wake brain regions in the context of Alzheimer's disease pathogenesis: a multi-modal, high-resolution neuroimaging approach

The longer average lifespan in our modern society is accompanied by a global increase in the prevalence of dementia, with Alzheimer’s disease (AD) being the most common cause. By 2050, the number of individuals with AD is expected to double in Europe and to triple worldwide reaching up to 153 million, highlighting the…

Data: CORDIS, © European Union

HE2024–20262 countries

Inlight · Process intensification towards sustainable wastewater treatment with phototropic biofilms

Wastewater treatment is essential for public health and environmental protection, yet conventional treatment technologies rely heavily on mechanical aeration, which consumes large amounts of energy and leads to substantial greenhouse gas emissions. Aeration alone can account for up to 70% of the operational energy dema…

Data: CORDIS, © European Union

HE2024–20272 countries

RestorAGING · A novel role for PGE2 signalling in promoting aged neuromuscular junctions reinnervation and counteracting sarcopenia.

As people live longer, we are facing a rapid rise in the number of older adults living with muscle weakness and loss of muscle mass, a condition known as sarcopenia. Sarcopenia increases the risk of falls and fractures, loss of independence, hospitalisation and long‑term care, with substantial costs for healthcare syst…

Data: CORDIS, © European Union

HE2024–20279 countries

PhotoCaM · Photosynthetic Antennas in a Computational Microscope: Training a new generation of computational scientists

Photosynthesis is a natural process that relies on harvesting solar energy and transforming it into chemical energy. In addition to its ecological importance, obtaining a better molecular-level understanding of photosynthesis, particularly of the light-harvesting process, is important because it is of key significance.…

Data: CORDIS, © European Union

HE2024–20272 countries

R-evolution · Why two and not one? Evolutionary consequences of maintaining individual genome copies in two separate nuclei

Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most devastating fungal diseases of wheat worldwide, posing a major threat to global food security.

Data: CORDIS, © European Union

HE2024–20272 countries

PnocMDDSex · Sex differences in BNST prepronociceptin-expressing neurons in modulating chronic stress-induced depressive-like behaviour in mice

Major Depressive Disorder, commonly known as depression, is a widespread mental health condition that affects millions of people worldwide. It's more than just feeling sad; depression can impact every aspect of a person's life, from their mood and interests to their ability to think clearly and even their basic bodily…

Data: CORDIS, © European Union

HE2023–20276 countries

SIMBAD · Statistical Inference from Multiscale Biological Data: theory, algorithms, applications

High-throughput experimental techniques have transformed the life sciences, enabling quantitative investigation of biological systems across scales, from molecules and cells to patients and populations. These technologies generate massive, high-dimensional datasets, including protein sequence families, spatial maps of…

Data: CORDIS, © European Union

HE2023–202815 countries

FutureData4EU · Training Future Big Data Experts for Europe

FutureData4EU is a Marie Skłodowska-Curie COFUND programme designed to address the growing demand for highly skilled researchers capable of navigating the societal, economic and ethical challenges posed by data-driven transformations in Europe. The project is embedded in the broader European policy context shaped by th…

Data: CORDIS, © European Union

HE2023–20277 countries

SameMultiPhys · Novel Biophysical Tools to Measure Multiple Parameters In The Same Cell

Mechanobiology is a dynamic and rapidly evolving interdisciplinary field focused on understanding how physical forces influence cells and tissues at multiple scales. This field holds immense potential for advancing healthcare and diagnostics, but its progress relies on the development of precise tools and methodologies…

Data: CORDIS, © European Union

HE2023–20253 countries

ChirPlasBiosensing · Self-assembled 2D Chiral Plasmene Nanosheets for Biomarker Detection Based on Surface-Enhanced Raman Scattering

Self-assemble 2D chiral plasmene nanosheets: ultrasensitive biomarker and chirality detectors. Surface plasmons are coherent and collective electron oscillations along the surface of a metal. In the case of plasmonic metal nanoparticles, this collective oscillation of conduction electrons yields remarkable optical prop…

Data: CORDIS, © European Union

HE2023–20253 countries

SIREN · Surface-enhanced Raman spectroscopy in liquid biopsy for breast cancer

Breast cancer is one of the most common cancers worldwide, and early detection is crucial for improving patient outcomes. However, current diagnostic approaches often rely on invasive procedures or lack sufficient sensitivity at early stages. The SIREN project aimed to address this challenge by developing advanced, lab…

Data: CORDIS, © European Union

HE2023–20252 countries

MemCage · Plasma membrane probes for photo-controlled release of signaling molecules

Introduction and the state-of-the art: A primary boundary between the extracellular environment and the cytoplasm, the plasma membrane (PM) of eukaryotic cells is a highly dynamic structure involves in diverse biological processes such as cellular uptake, neural communication, muscle contraction, and cell trafficking a…

Data: CORDIS, © European Union

HE2023–20275 countries

WhyNotDry · Toward consolidation of germplasm and cell reversible drying through knowledge transfer.

Project Context WhynotDry aims to develop alternative storage methods for genetic banks by inducing reversible drying in cells and germplasm (spermatozoa). The goal is to create low-cost, low-carbon biobanks that reduce reliance on liquid nitrogen (LN), which is effective but expensive, facility-dependent, and carbon-i…

Data: CORDIS, © European Union

HE2023–20275 countries

BIOSMALL · Identification of subtype-specific biomarkers in small cell lung cancer

Lung cancer is one of the most frequently diagnosed malignancy worldwide and the leading cause of cancer-related mortality. Historically lung cancer is divided into two major categories: non-small-cell lung cancer (NSCLC, ~85%) and small-cell lung cancer (SCLC, ~15%). SCLC is infamous within the field of oncology for b…

Data: CORDIS, © European Union

HE2023–20262 countries

URBANE · Early-life URBAN environmental exposures and childhood multimorbidity: An Exposome-wide approach

More than half of the world’s population lives in cities, and this proportion is expected to increase to nearly 70% by 2050. While urban living offers many benefits, it also exposes people to environmental factors such as air pollution, noise, heat, traffic and limited green spaces. These exposures are known to affect…

Data: CORDIS, © European Union

HE2023–20252 countries

MultiPly · FMO1 Multifunctionality for improved Plant health

‘MultiPly: FMO1 Multifunctionality for improved Plant health’ The project 'MultiPly' will investigate the extended role and evolution of the critically important FMO family in plants and examine the physiological mechanisms of how this enzyme can improve plant resilience under environmental stress conditions. The long-…

Data: CORDIS, © European Union

HE2023–20262 countries

CADASIL-iMATTR · Investigation of Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy (CADASIL) using induced pluripotent stem cell modelling and targeted therapeutic research

This project aims to understand the underlying cause of stroke and cognitive impairment. These conditions can be caused by changes in the blood vessels of the brain. Patients with a genetic condition known as CADASIL or Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy suffer fr…

Data: CORDIS, © European Union

HE2023–20252 countries

ClearPath · Amyloid-β clearance in Alzheimer's disease: Unravelling the role of endocytic pathways of endothelial cells

Alzheimer’s disease (AD) is characterized by the progressive extracellular accumulation of β-amyloid peptide (Aβ) in the brain, leading to the formation of amyloid plaques. Aβ deposition is a major risk factor for the onset and progression of AD. While research has traditionally focused on neurons, glial cells, and ast…

Data: CORDIS, © European Union

HE2023–20252 countries

GBV_COP_SOC · Exploring Complex Realities Around Gender Based Violence, Multiple Legal Orders and Role of Police in Addressing GBV Cases in Pakistan and Pakistani Immigrant Community in Norway

Gender-Based Violence (GBV) within Pakistani society and among Pakistani immigrant communities in Norway is a serious issue. The study examined how entrenched patriarchal norms and power imbalances perpetuate violence against marginalized groups, particularly women, across both national and diasporic contexts. Hosted b…

Data: CORDIS, © European Union

HE2023–20252 countries

MAREE · Mechanisms of Antibiotic Recalcitrance in ESKAPE pathogens

The discovery of antibiotics in the late 1920s was one of the biggest achievements in medicine. However, the rise of antimicrobial resistance (AMR) now threatens this progress. The World Health Organization (WHO) warns that by 2050, antibiotic-resistant infections could cause 10 million deaths per year and cost the glo…

Data: CORDIS, © European Union

HE2023–20252 countries

KinSiGHT · Kinship Systems in Gyalrong: History and Transformation

This project investigates the unique kinship systems and family structures among ethnic groups in the Hengduan Mountains of Southwest China, with a specific focus on Gyalrongic-speaking communities in Western Sichuan. This region is characterized by ethnolinguistic diversity and linguistic conservatism, which coexist a…

Data: CORDIS, © European Union

HE2023–20252 countries

DAFNE · Delivery of Small RNAs by Functional Hydrogel Nanoparticles to Improve Osmotic strEss Tolerance in Plants

Climate change is having a huge impact on the worldwide crop yield with a considerable decreasing of crop production every year (between 20% to 40% of global crop production). Plant genetic improvement is continuously looking for novel approaches to obtain climate-ready crops, preserving the biodiversity and food safet…

Data: CORDIS, © European Union

HE2023–20278 countries

BioacAI · Bioacoustic AI for wildlife protection

Biodiversity loss is ranked as one of the top 5 risks globally, both in impact and likelihood. Anticipated significant declines in bird and insect populations could trigger profound ecological catastrophes. Yet data for monitoring biodiversity change remain incomplete.

Data: CORDIS, © European Union

HE2023–20278 countries

YAF · Yeast-based solutions for sustainable Aviation Fuels

Aviation is one of the most challenging transport sectors to decarbonise due to its reliance on high-energy-density liquid fuels and the absence of viable large-scale alternatives in the near future. Drop-in sustainable aviation fuels (SAF) represent a short- to medium-term solution, as they are fully compatible with e…

Data: CORDIS, © European Union

HE2023–202711 countries

CryoStore · Innovation in germplasm cryopreservation for improved animal breeding and the conservation of Europe's livestock biodiversity

There is growing international concern about the continued loss of animal biodiversity. While most attention has focused on iconic species, the conservation of Europe’s numerous native breeds of farm animals and the need to maintain genetic diversity within breeds, has largely been overlooked. Animal production systems…

Data: CORDIS, © European Union

HE2023–20274 countries

INNOVATION · Ion channels in erythrocytes: A novel understanding from regulation of erythropoiesis and physiological function to diagnostic measures and therapeutic concepts

Erythrocytes (red blood cells) make up 84% of all human cells and are exposed to a range of physical and chemical stimuli during circulation, such as pressure changes, shear stress, and hormonal fluctuations. These stimuli are processed by ion channels, which are crucial for erythrocyte function. Despite their importan…

Data: CORDIS, © European Union

HE2023–20252 countries

RedoxBoost · Boosting stress resilience of Arabidopsis by heterologous expression of a selenocysteine containing glutathione peroxidase

Agricultural productivity is increasingly threatened by a range of abiotic stresses—including flooding, prolonged drought, and heat waves—as well as biotic stresses such as bacterial, fungal, and insect infections. These stressors contribute significantly to crop losses and pose a serious risk to global food security.…

Data: CORDIS, © European Union

HE2023–20252 countries

BionovFOOD · GREEN PROCESSING AND VALORIZATION OF ORGANIC BY-PRODUCTS OF DISTILLERIES, AS NOVEL APPROACHES FOR CLIMATE-SMART PROTEIN APPLICATIONS FOR ALTERNATIVE FOOD AND CIRCULAR BIO-ECONOMY

Food systems are under growing pressure to deliver safe, healthy, accessible, and affordable nutrition for a rapidly expanding global population, projected to reach 10 billion by 2050. This challenge is intensified by climate change, pandemics, economic instability, and rising demand for dietary supplements. Meeting th…

Data: CORDIS, © European Union

HE2023–20253 countries

AROUSE · Assessing the impact of climate fluctuations on hibernation phenology using novel dental biomarkers

Recent increases in global temperatures have been severely affecting the hibernation patterns of small mammals. Many species now tend to emerge too early in spring, potentially altering individual fitness and posing risks to population viability. Hibernation is a key physiological mechanism of metabolic reduction that…

Data: CORDIS, © European Union

HE2023–20252 countries

ViROSCa · Deciphering the roles of reactive oxygen species and calcium during viral infection in Arabidopsis

Viral diseases are a major and growing threat to global food security, responsible for severe crop losses and rising pesticide use. One such emerging pathogen is Plantago asiatica mosaic virus (PlAMV), a potexvirus capable of infecting a wide range of hosts and spreading rapidly between plant cells. Once a virus enters…

Data: CORDIS, © European Union

HE2023–20277 countries

NERVSPAN · Molecular Dynamic of Neurons during C. elegans Lifespan

Neurons form intricate networks and communicate with each other through synaptic protein complexes. Neuronal excitability and signal propagation are governed by transcriptional and post-transcriptional regulation of gene expression as well as by precise protein trafficking. With the support of the Marie Skłodowska-Curi…

Data: CORDIS, © European Union

HE2023–20264 countries

AREB · The Arabic Roots of European Biology

AREB investigates how Avicenna (Ibn Sīnā, d. 1037) articulated a new paradigm for biological inquiry centred on the organic body—a multifaceted concept encompassing the full range of biological diversity. This paradigm integrates all living forms and stages, including not only the supposedly standard male body but also…

Data: CORDIS, © European Union

HE2023–20277 countries

Eco2Wine · Natural microbial interactions in winemaking-associated ecosystems as a tool to foster wine innovation

Preserve and Use Biodiversity While Promoting Sustainable Wine Production: The Eco2Wine Project The wine industry faces growing challenges across environmental, economic, and societal dimensions. Environmental concerns include the impacts of climate change, overreliance on chemical inputs, and unsustainable resource ex…

Data: CORDIS, © European Union

HE2023–20252 countries

MicroCoFE · A Microscale View to Coral Function in a Changing Environment

Context Coral reefs are highly valuable ecosystems that support biodiversity, coastal protection, and millions of people worldwide. However, they are rapidly declining due to climate-driven stressors such as warming, acidification, and deoxygenation. These factors disrupt coral physiology and lead to bleaching and mort…

Data: CORDIS, © European Union

HE2023–20252 countries

CRMS · Microfluidic Diffusion-based Chiral Resolution

Context: Homochirality is a fundamental feature of animate matter, and nearly all biological processes occurring in nature are stereospecific, i.e., responsive to only one type of handedness of the chiral molecule. Most drugs are chiral and must be administered as a single enantiomer because their enantiomeric form may…

Data: CORDIS, © European Union

HE2023–20252 countries

GlycoMap · Integrated Glycomics for Cancer Precision Medicine

Tissue heterogeneity is fundamental for the development of multicellular organisms but presents considerable complexity for our understanding of biology and disease mechanisms, including cancer. One of the largest sources of tissue heterogeneity arises from post-translational glycosylation of proteins (attachment of a…

Data: CORDIS, © European Union

HE2023–20253 countries

COMAL · Cuisine(s) of the Ancient Maya across the Lowlands: Reconstructing Plant Diets through Molecular and Imaging Approaches

The transformation of plants into foodstuffs can be regarded as a form of cultural expression, and the culinary practices that accompany this transformation have the capacity to serve as indicators of social and cultural identities within the archaeological record. The COMAL project (2023-2025) sought to employ innovat…

Data: CORDIS, © European Union

HE2023–20277 countries

IDPro · Intrinsically disordered proteins in health and disease: mechanisms, molecular context and opportunities for drug discovery

Nearly 40% of the human proteome does not fold into well-defined structures. Instead, these proteins, or parts of proteins, are intrinsically disordered, meaning they lack a fixed structure. These intrinsically disordered proteins (IDPs) play vital roles in cell communication, regulation, and adaptation.

Data: CORDIS, © European Union

HE2023–20252 countries

MFCBioFactory · Novel bioelectrochemical factory system for energy production and treatment of industrial wastewater: Electroactive and non-electroactive microbiome

Industrial wastewater treatment is one of the greatest environmental and technological challenges of our time, particularly when dealing with high-salinity effluents generated by sectors such as the canned food industry. These wastewaters contain high levels of organic matter, nutrients, and salts, making conventional…

Data: CORDIS, © European Union

HE2023–20252 countries

PeriCarb-EFA · Effects of extreme flow changes on periphyton biofilm and carbon cycling in Alpine streams

Climate change is increasingly altering the frequency and intensity of extreme hydrological events, such as droughts and floods, with profound consequences for freshwater ecosystems. In mountain regions, these changes are occurring faster than in most other biomes. Alpine catchments are experiencing reduced snow accumu…

Data: CORDIS, © European Union

HE2023–20252 countries

PaedsSeq · Nanopore sequencing of cell-free DNA for the sensitive detection, molecular profiling and monitoring of childhood cancers

Paediatric cancer is the leading cause of death in children post infancy in the Western world. Solid tumours, including tumours of the central nervous system (CNS), neuroblastomas, and bone and soft tissue sarcomas, are amongst the poorest outcome cancers in children (5-year survival rates <50%). These account for >50%…

Data: CORDIS, © European Union

HE2023–20252 countries

EcoPDI · Earth-abundant metal-containing photosensitizers for sustainable photodynamic inactivation in plant protection and food safety

Global food insecurity is one of the current urgent problems, since around 343 million people are now facing high levels of it, notably in Gaza and Sudan, but also in pockets of South Sudan, Haiti and Mali. In addition, agriculture is increasingly under pressure to reduce pesticide use, ensure food safety and protect t…

Data: CORDIS, © European Union

HE2023–20263 countries

PLANTID · Conserved develoPmentaL trAjectories chaNnelling laTeral root prImorDium morphogenesis

One of the most pressing challenges of the 21st century is sustaining agricultural productivity in the face of mounting environmental stress. Root systems are central to this challenge, as they anchor plants in the soil and control the uptake of water and nutrients. Their spatial configuration, referred to as root syst…

Data: CORDIS, © European Union

HE2023–20262 countries

ReTouch · Physics-based Remote Touch

The ability to feel is central to how humans interact with the world. We rely on our sense of touch to hold a pen, find keys in a pocket, or judge the texture and softness of an object often without needing to look. In contrast, most robotic systems still operate largely by vision alone.

Data: CORDIS, © European Union

HE2023–20252 countries

EarthSea · Ecocritical Approach to Land Subsidence in Italy's Po Delta region

EarthSea investigates the ways in which literature and visual media addressed forms of water-soil relationships– with a particular focus on land subsidence – in the context of the Po Delta in Italy. The Po Delta, a significant anthropogenic river delta in Europe, endured a long history of disruptive soil transformation…

Data: CORDIS, © European Union

HE2023–20252 countries

MICROCOSMS · Exploring microbial community stability across mutational spectra

Mutualistic interactions – where both species benefit – lie at the core of many human-relevant microbial communities, such as polymicrobial infections, the human-, plant-, and animal-associated beneficial microbiomes, and synthetic microbial communities in biotechnology. However, previous work has suggested that mutual…

Data: CORDIS, © European Union

HE2023–20262 countries

SimViRNA · Multiscale Simulations of HIV capsid assembly and RNA

This project aims to establish new approaches toward large-scale simulations of biomolecular systems. We concretely seek to develop bottom-up coarse-grained models for the immature HIV CA-SP1 lattice including protease dimers as well as for RNA systems. Proteolytic cleavage of the CA-SP1 junction is an essential proces…

Data: CORDIS, © European Union

HE2023–20252 countries

MINIMA · Microbial navigation strategies in ecologically relevant porous media

Microorganisms may be too small to see, but they are everywhere around us—and inside us. In fact, the number of bacteria living in our body is roughly the same as the number of human cells we have. These tiny companions keep us healthy by aiding digestion, defending against harmful germs, and even shaping how we feel.

Data: CORDIS, © European Union

HE2023–20252 countries

ARCHAIC · Diversity of bacteriophages in the ancient human microbiome

The ARCHAIC project addressed a critical gap in microbiome research: the lack of evolutionary insight into the human virome, specifically bacteriophages (phages), through deep-time metagenomic analyses. Previous paleogenomic efforts primarily focused on bacterial components, leaving viral fractions, especially phages,…

Data: CORDIS, © European Union

HE2023–20252 countries

ORION · HydrOdynamics & biomechanics of canceR cell mIgration in heterOgeNeous media

Metastasis—the spread of cancer from a primary tumor to distant organs—remains one of the most complex and least understood aspects of cancer progression, responsible for over 90% of cancer-related deaths. A key step in this process is the migration of circulating tumor cells (CTCs) through the heterogeneous and mechan…

Data: CORDIS, © European Union

HE2023–20252 countries

DNAPC4ImunoMol · DNA modules as communicators in tumor immunomodulation

Certain diseases present themselves as a complex molecular scenario. In these diseases, of which the most important examples are cancer and autoimmune diseases, a single treatment, e.g. a drug, only works under strict conditions.

Data: CORDIS, © European Union

HE2023–202711 countries

GlyCanDrug · A training network on the design of precision therapeutics that target key glycan motifs implicated in cancer

Glycoscience, the interdisciplinary study of the structure, function, and biology of carbohydrates (or glycans) and their roles throughout biology, has made significant strides in the past decade, putting in the spotlight the key role of glycan-motifs on cancer glycocalyx (essentially a "sugar coat" surrounding tumor c…

Data: CORDIS, © European Union

HE2023–20278 countries

MMM · Medicine Made to Measure.

MMM is an intersectoral, innovative training network that receives funding from the European Commission (2023-2027) as part of the HE MSCA programme. It consists of nine beneficiaries, hosting 10 doctoral students, plus 14 associated partners providing training, PhD enrolment or secondment opportunities. MMM stands for…

Data: CORDIS, © European Union

HE2023–20278 countries

SPIDoc's · The Next Generation MS SPIDoc’s

SPIDocs is an interdisciplinary and intersectoral doctoral network comprising 7 Beneficiaries and 7 associated partners, and 10 Doctoral Candidates (DCs). Among the partners, three are industry partners, of which one is a beneficiary hosting two DCs, SPIDocs developed ad-hoc training programme covering the different di…

Data: CORDIS, © European Union

HE2023–20252 countries

T2D-EOMICS · High throughtput electrophysiological measurements coupled with transcriptomics to reveal cellular dysfunction in type 2 diabetes

Type 2 diabetes is a long-lasting condition in which the body loses its ability to regulate blood sugar levels. The pancreas is the organ responsible for this function. One of the main reasons for the progression of type 2 diabetes is that the pancreas becomes less capable of producing insulin.

Data: CORDIS, © European Union

HE2023–20252 countries

DISEQ · The Drought Impact on the Climate Benefit of Carbon Sequestration

Human activities have led to rising levels of carbon dioxide in the atmosphere, altering how carbon moves through the Earth’s systems and profoundly affecting the global climate. This shift changes the delicate balance between carbon, water, and energy that regulates both the atmosphere and ecosystems. While forests an…

Data: CORDIS, © European Union

HE2023–20273 countries

Wide-Band Ephys · Large-scale and wide-band brain dynamics mediating memory consolidation in the freely moving rat

Dementia is a major healthcare challenge worldwide due to its high incidence and its strong impact on the life quality of patients and on society as a whole. Development of treatments for the mitigation of memory impairment in patients with dementia has proven very challenging, partly due to our limited understanding o…

Data: CORDIS, © European Union