immunology

GALTRAIN · Exposure to micro-organisms and suppression of allergic diseases: A European research training scheme

6 partners · 3 countries

ACUP · Functional analysis of new acute phase proteins

4 partners · 4 countries

IMMUNOBIOTA · Tools for integrated studies of the immunoregulatory properties of commensal microbiota

6 partners · 6 countries

LEVITATES · Targetting VAP-1 to treat chronic inflammatory liver disease

2 partners · 2 countries

IMMUNOKINASE-B · Understanding a severe thymus phenotype in a PKB mouse model: role of specific PKB isoforms in thymus and T cells development

IDEA · Immunoregulation during early antimicrobial responses

OPINF · The role of opioids in protective immune response of carp

SHP-1 RGULATION · The regulation of SHP-1 tyrosine phosphatase in B cell antigen receptor signaling

PROTEUS · The role of the intracellular peptidases in the immune system and in the cellular metabolism

LY49-AUTOIMMUNITY · Regulation of immune responses and autoimmunity by activating and inhibitory NK receptors expressed by T lymphocytes: role of ITAM versus ITIM signal balance

GENETIC BARCODING · Determining the relationships between haematopoietic lineages using genetic barcoding

ANTILEUKEMIA T CELLS · Redirecting Cytotoxic T Lymphocytes towards Leukemic antigens

NALP3 AND MDP · Role of the NALP3-inflammasome activation by muramyl dipeptide in vivo

LXRNEUROINFLAMMATION · Anti-inflammatory and anti-apoptotic effects of LXR/RXR agonists in the central nervous system

BACTERIA IBD · Identification of the mechanisms by which Helicobacter induces intestinal inflammation

GADD45 AND P38 · Role of the p53-effector gene Gadd45 as tumor suppressor and/or autoimmune disease suppressor gene

RECEPTEUR · Cytokine receptor traffic, signalling and human disease

9 partners · 7 countries

NLRS IN IMMUNITY · NLR-proteins in Immunity and Inflammation

NK DEFENSE AND THERAPY · Natural killer cell-mediated anti-viral and anti-tumour defence and therapy: Integrated research training in molecular medicine, bioinformatics and issues of patent application and the SME biotech business

12 partners · 7 countries

CYTOLYTIC SYNAPSE · Regulation of cytotoxic T lymphocyte activity at the lytic synapse

VISUALIZING IMMUNITY · Dynamics of T cell activation and anti-tumor T cell activity in vivo

IMMUNADAPT · Role of the Nck adaptor proteins in adaptive immune responses

PORCINE CD200 · Study of the CD200/CD200R pathway in the pig-to-human setting to elucidate the molecular bases of xenograft rejection and develop approaches that promote xenograft survival.

ERAP1 · Structural basis and specificity of antigenic peptide trimming by the newly discoverd ER aminopeptidases ERAP1 and ERAP2