immunology

RepliFate · DNA replication at the heart of cell fate decisions and cancer development

21 partners · 7 countries

engineereD to Clear · Investigation on the vaccination potential of IL4i1 deficient dendritic cells in Chronic lymphocytic leukemia

MirrorBody · Discovery, total chemical synthesis, and validation of “mirror-image” D-Nanobodies

Th17 tissue metab · Metabolic imprinting of Th17 cells in disease pathogenesis

2 partners · 2 countries

TOLERATE · An integrated approach to restore tolerance in autoimmune disease

18 partners · 9 countries

RePLASTIC · Uncovering the Regulators of Cellular Plasticity by Direct Reprogramming

ReCHISVac · Experimental vaccinology, revealing unnatural signatures of protection by repeat controlled human schistosome infection.

3 partners

SMiPAX4 · Signalling of Minor Pocket Agonists at CXCR4

2 partners

LactoVES · Immunomodulatory properties of L. plantarum extracellular vesicles in airway allergy

2 partners · 2 countries

ProAPP · PROTAC-driven Protein degradation by Proteasome during Antigen Processing and Presentation (ProAPP)

IMMUNOBAT · Elucidating the crosstalk between the immune system and brown adipose tissue in humans

NatureSToll · Nature Self-medication: Poisoning the microbes a Toll for wildlife

INTERCONNECTION · Inter-tissue communication during nematode infections: role of dermal γδ17 T cells

SNAP-Vax · Engineering a Sugar-targeted Nucleic Acid delivery Polymer to understand and enhance vaccination by self-amplifying RNA

IMPROVING-GT · Innovative strategies to increase engraftment of engineered hematopoietic stem cells and bypass genotoxic conditioning, toward the next-generation gene therapy

BreaKer · Dissecting how breast cancer-associated inflammation shapes invariant natural killer T cell activity during metastatic progression

Chemical Mutagenesis · a powerful tool for the creation of a library of nanobodies

GIPTRAP · Therapeutic potential of recombinant antibodies to neutralize immunogenic peptides in celiac disease

ENDOLOGISTIC · Endocytic logistics of defense signaling in plants

MACROVALVE · Understanding the role of macrophages in the structural degeneration of bioprosthetic heart valve leaflets

2 partners · 2 countries

IMPRINT · Immunological and Microbiota Priming of the Response to Infection

PAMSEQ · High-Throughput Mapping of Antibody Sequences to Antigen Specificity in Placental Malaria

2 partners · 2 countries

Allo-THYTECH · Development and implementation in clinical practice of the allogeneic use of thymus-derived regulatory T cells (thyTreg) as a cell therapy to suppress harmful immune responses

TOXOSHEEP · Study of the molecular mechanisms underlying Toxoplasma-induced early abortions in a pregnant sheep model of infection