medicinal chemistry

LysoMod · Genetic and Small Molecule Modifiers of Lysosomal Function

14 partners · 9 countries

in3 · An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment

19 partners · 11 countries

FLUORODRUGS · Smart Theranostic Agents for the Tumour Microenvironment

DesignerAntibiotics · Towards the prevention of aminoglycoside antibiotic-related deafness

2 partners · 2 countries

TaGFrag · Stabilising Protein-Protein Interactions: A Target-Guided Fragment-Based Approach

TRACT · Training in Cancer Mechanisms and Therapeutics

12 partners · 6 countries

LSD-CortLVPC · Applying voltage-imaging techniques to visualise the effect of lysergic acid diethylamide (LSD) on cortical layer V pyramidal cells and its adaptation during tolerance development

CHIKV-FBDD · Structural investigation into functionality of Chikungunya virus nsP2 in replication complex and screening of small molecules for its inhibition

PET3D · PET Imaging in Drug Design and Development

10 partners · 7 countries

CF_struct · High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator

HeartAtaK · Targeting the Anti-Target: From Structure to Drug in the heart Kv11.1 channel

AEGIS · Accelerated Early staGe drug diScovery

24 partners · 9 countries

ISOTOPICS · ISOTOPIC LABELING FOR DRUG INNOVATION

13 partners · 5 countries

MEMBRANEPROT · Membrane proteins – development of new computational approaches and its application to G-Protein Coupled Receptors

jamclay · Chemical Tools to Probe the Role of Bromodomains in the Parasite Trypanosoma cruzi

ChemoBOOM · Development of Palladium-Labile Prodrugs for Bioorthogonally-Activated Chemotherapy

APCINTERACTIONS · Molecular basis for securin and cyclin ubiquitylation by the anaphase-promoting complex (APC/C)

CHELALZ · Multitarget compounds with therapeutic potential against Alzheimer disease: Design and in vitro studies

NPL · Synthesis of Natural Product Like Compounds for Drug Discovery

GLYCOVAX · A training network for the rational design of the next generation of well-defined glycoconjugate vaccines

12 partners · 8 countries

MOGLYNET · Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study

13 partners · 8 countries

RENALTRACT · Development and disease of the renal tract

9 partners · 4 countries

ORGANO-GOLD CAT · Merging organo- and gold-catalysis to design cascade reactions: a shortcut toward molecular complexity

C-Xaq · Cross-Coupling (C-X): Pioneering Mild Aqueous Cross-Coupling Methodologies to Enable Selective Functionalisation and Diversification of Halogenated Natural Products