medicinal chemistry

154 projects

H2020Individual fellowship2015–2017United Kingdom

MACROIMAGING · Specific Fluorogenic Peptides for Imaging Metastasis-associated Macrophages

H2020Individual fellowship2015–2017Spain

silvercatpharma · from gold to silver: streamlining metal-catalysed cross-coupling reactions

H2020Individual fellowship2015–2017United Kingdom

MBLIs · New Approaches to Metallo-β-Lactamase Inhibitors

H2020Individual fellowship2015–2017United Kingdom

Amine-FUNC · Amine-Directed Diverse C(sp3)-H Functionalization

H2020Individual fellowship2015–2017United Kingdom

ISOTRAPSS · Isoform specific inhibition by transient protein state stabilization

H2020Individual fellowship2015–2017United Kingdom

Bump-BET · Bump and Hole approach to elucidate function of individual bromodomains of BET proteins

H2020Individual fellowship2015–2017Poland

FAST-RAP · Structure-function studies of the human FASTK family of mitochondrial proteins with putative novel RNA binding domains – the helical FAST motifs and the small RAP domain

H2020Individual fellowship2015–2017United Kingdom

Pharmcophore-DOS · Pharmacophore guided diversity-oriented synthesis and its application in discovering inhibitors of protein-protein interactions between RAD51 and BRCA2

H2020Doctoral network2015–2018Italy

INTEGRATE · Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets

14 partners · 8 countries

H2020Doctoral network2015–2019Netherlands

ANTIVIRALS · European Training Network on Antiviral Drug Development

13 partners · 7 countries

H2020Doctoral network2015–2018Germany

MAGICBULLET · Peptide-Drug Conjugates for Targeted Delivery in Tumor Therapy

14 partners · 4 countries

FP7Individual fellowship2014–2017Spain

MEMBRANELIPIDTHERAPY · Membrane lipid composition as new antitumor therapeutic target: sphingomyelin synthase (SGMS) at the basis of Minerval® mechanism of action and design of new Minerval®-related drugs

FP7Individual fellowship2014–2016United Kingdom

NEUPROTALL · The role of neutrophils and their proteases in the pathology of allergic airway disease

FP7Individual fellowship2014–2016Germany

POL2-CCR · Structure-function analysis of mRNA metabolism by Ccr4-Not

FP7Individual fellowship2013–2015United Kingdom

orthoPROTACS · Design of orthogonal molecular probes targeting engineered von-Hippel Lindau (VHL) E3 ubiquitin ligase for the control of intracellular protein levels

FP7Individual fellowship2013–2015United Kingdom

HKMTIs · Computer-aided Design and synthesis of inhibitors of EED-EZH2 interaction as a novel approach for anticancer therapy

FP7Individual fellowship2012–2014Netherlands

mechFXR · Towards FXR-mediated therapeutic intervention: Understanding how FXR integrates metabolic, endocrine and inflammatory signaling

FP7Individual fellowship2011–2013Belgium

Synapses FXS · Characterization of the molecular components of synapses in Fragile-X mental retardation syndrome: new insights into the FMRP regulatory mechanisms

FP7Individual fellowship2011–2013Netherlands

TN-SEQ · Identification of genetic determinants involved in Streptococcus pneumoniae pathogenesis

FP7Individual fellowship2011–2013Germany

MolecularDoctors · RNA-codified release of cytotoxic peptides from PNA prodrugs as a new therapeutic approach to cancer

FP7Individual fellowship2011–2014United Kingdom

ICSTH · An Integrated Computational and Spectroscopic Investigation of the Enzyme Mechanism of Tryptophan Hydroxylase

FP7Reintegration grant2010–2013Italy

NAPE-PLD · Structural and functional insight into the biosynthesis of endogenous lipidic messengers by the N-Acyl Phosphatidylethanolamine Phospholipase D (NAPE-PLD)

FP7Individual fellowship2010–2012Slovenia

COSPRODYN · Computational Studies of Proton Dynamics in Hydrogen Bonded Systems and Enzymes

FP7Individual fellowship2010–2012Denmark

ALOE-DIVERSITY · Phylogeny and ethnobotany: Testing predictive approaches to plant drug discovery in the genus Aloe L. (Asphodelaceae)