drug resistance

PROTACs · Design, synthesis and biological evaluation of PROteolysis-TArgeting Chimeric (PROTAC) molecules as anticancer agents

valOH · Assessing the social value of One Health approaches

DEFCOMANT · Establishing defined communities of Antarctic soil bacteria as potential sources of antimicrobials

BactDrugConj · Bacteriocin-mediated Import of Active Molecules

PERSIST · Antibiotic persisters during infection: a tail of intestinal dominion

2 partners · 2 countries

PhotoLiB · Photoswitchable amphiphilic lipids: a photopharmacology strategy to combat drug-resistant bacterial infections.

2 partners

Phage POWER · Plasmid-Specific Bacteriophages to mitigate the Spread of Antimicrobial Resistance in Used Water & the Environment (Phage POWER).

PROBYDE · Probing the bypassability of genetic constraints in drug-resistance enzymes

REDTEAR · The Role of free Extracellular DNA in determining The Environmental Antibiotic Resistome

MiTuMi · Bioengineered Matrices Mimicking the Lung Tumor Microenvironment

DIMEvAR · Impact of medical drugs on the evolution of human microbiome function and antimicrobial resistance development

SNiB-cdG-P · Global mapping of second messenger c-di-GMP signaling networks in bacteria using proteomics

FULLREMOVAL · Feasibility of ULtrafiLtration membranes for REMOVAL of antibiotic resistant bacteria and antibiotic resistance genes from secondary effluents from wastewater treatment plants

INNOTARGETS · Innvative approaches to identification of metabolic Targets for antimicrobials

9 partners · 6 countries

EvoSpa · Structured, not stirred: experimental evolution in programmable antibiotic landscapes

SlowDisasters · Political Dynamics of Slow-Onset Disasters: Contrasting Antimicrobial Resistance (AMR) and Ebola Responses

G4-AntiBac · Targeting G-quadruplex DNA Structures in Bacteria to Combat Antimicrobial Resistance

CAGECONTROL · Identification and manipulation of factors that control Shigella flexneri entrapment in septin cages.

IDYEA · Antimicrobial resistance in engineered wastewater systems – Predicting the impacts of dynamic exposure levels to antimicrobial agents on AMR attenuation and amplification

THERMUCNA · Thermoresponsive and mucoadhesive nanogels for intramammary administration of antimicrobial compounds to be employed in bovine mastitis treatment

PSIPCancer · Role of PSIP1 in prostate cancer development and drug resistance

MITHAML · Exploring the role of Metabolic IntraTumoral Heterogeneity in drug resistance of Acute Myeloid Leukemia in vivo

2 partners · 2 countries

AmCaLiStat · Modular Design of Bacterial Lipid Mimics for Next-Generation Antimicrobials

GLYCO-WAY · Glycomics of Winery Antimicrobial Yeast

2 partners · 2 countries