drug discovery

FungiFeS · Iron-sulphur cluster biogenesis: deciphering new molecular mechanisms and exploiting novel antifungal and fungicide targets

DELCAT · Catalysis toward platinum substrates for drug delivery

USP2-TD · Revolving around the ubiquitin‒proteasome system: USP2-targeted degrader

GPR84 · Biased Agonism of GPR84 as a Novel Dual Anti-inflammatory and Pro-repair Mechanism

G4-mtQSAR · Identifying new anti-cancer drugs by computational multi-target approaches targeting the Gquadruplex DNA

PhotoPhos · Photoinduced Decarboxylative Phosphorylations

LateCPC · Late-stage C–H bond construction of cyclopropanes to impact drug discovery

ALISE · Anti-Cancer Light-Controllable Antibody-Peptide Conjugates

6 partners · 4 countries

PORTable STaNDOuTs · Perfused Organs-on-a-Chip integrated with TEER measurement technique: A novel approach towards studying non-targeted drug induced organ toxicity

FLAMMES · On-chip metasurface-based neuroimaging platform toward high-throughput drug screening in freely behaving animal

MAP-AD · A multimodal approach to accelerate drug discovery and development in Alzheimer’s disease

2 partners · 2 countries

TS4NC · Therapeutic S4N Chelation targeting Alzheimer's Disease.

GHRH neurons · Generating growth hormone-releasing hormone neurons from human embryonic stem cells

MIM · Molecular Imaging of Microglia

MicroProtLip · New microfluidic tools for characterization of protein-lipid interactions

UltraRamanomics · High Content Microanalytical Ramanomics for Ultraquantitative Phenotyping of Individual Stem Cells and Bioengineered Organoids

MITiC · Molecules Inhibiting Translation in Cancer cells

VibMolCryst · Vibrational Spectroscopy for Molecular Crystals via Quantum-Mechanical Embedding Methods

HTS MALDI-TOF MDD · MALDI-TOF mass spectrometry metabolite screening assays for drug discovery in human disease

SmartHeart · SmartHeart, a 3D in vitro assay for improved assessment of cardiac drug efficacy and toxicity

STARSS · Super Time-resolved Fluorescence Anisotropy with Switchable States

BISBORONDYKAT · Asymmetric Csp3 – Csp3 Suzuki−Miyaura Coupling Employing 1,1-Bisboryl Alkanes

PHOTO-CYCLE · Photocatalysis in Drug Discovery - Asymmetric Preparation of Bioactive Chiral Lactones and Cyclohexanols

RECOBIN-PROTACs · Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy