gene therapy

FSHD ANIMAL MODEL. · An animal model to develop therapeutic strategies for facioscapulohumeral muscular dystrophy, FSHD

VEGFALS · Therapeutic role of different VEGF members on neuron and muscle degeneration

NICOTINIC RECEPTORS · Viral vector and RNAi strategies to determine the role of beta2 containing nicotinic receptors in aversive learning

DROSOPHILA TELOMERES · Drosophila Telomere Heterochromatin: Gene silencing and Telomere targeting

APOLIPOPROTEIN E · Functional interactions of apolipoprotein E with the ABCA1 lipid transporter and the SR-BI HDL receptor that affect cholesterol homeostasis in circulation and brain

CYTOLYTIC SYNAPSE · Regulation of cytotoxic T lymphocyte activity at the lytic synapse

SGT FOR GVL · Safe and effective immunotherapy of leukaemia with suicide gene-modified human T lymphocytes retaining anti-minor histocompatibility antigen reactivity

SEMAPHORINSANDCANCER · The role of semaphorins and plexins in cancer progression and angiogenesis

ALLELO-SIGNALLING · Dissection of signal transduction cascades regulating inter and intra-species interactions among phytoplankton assemblages in the marine environment

TRANSFECTAZINE · Low-toxicity azine-based cationic lipids for gene transfection

STEROTRANS · Anion Transport by Steroid-Based Synthetic Channels

RETNET · European Retinal Research Training Network

7 partners · 5 countries

BIFIDOGT · Towards gene therapy using Bifidobacterium as gene delivery system

GENE THERAPY PARKINS · Gene therapy for treatment of Parkinson's disease : functional and cellular evidence

BENJAMIN MARTIN · Dynamic and targeted vectors for gene transfer

Spatio-temporal controlled gene delivery and expression for non viral gene therapy

Development of triggered endosomolysis mechanism for improved gene therapy

Assessing the potential of b-globin replicating espisomal vectors for gene therapy of the haemoglobinopathies

Confinement of dna in thin liquid films. Study of the electrostatic interactions and of the influence of condensing agents

Optimisation of retroviral vectors for gene transfer to human pluripotenthematopoietic cells and application to chronic granulomatous disease

Identification of fgf-stimulated signalling pathways critical for angiogenesis

2 partners · 2 countries

Biological role of the atf2 transcription factor. Molecular mechanisms involved in atf2 regulated transcriptional activation

2 partners · 2 countries

Gene therapy for mucopolysaccharidosis - adeno-associated virus and lentivirus as vectors for muscle, liver, central nervous system and bone marrow

2 partners · 2 countries

Gene therapy of rheumatoid arthritis by means of cytokine modulation

2 partners · 2 countries